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"Post-Kasai Portoenterostomy Cholangitis: What Have We Learnt So Far?".
J Clin Exp Hepatol
December 2024
Department of Pediatric Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.
Post-Kasai portoenterostomy (KPE) cholangitis is one of the most common complications that has a negative impact on liver function and native liver survival. Early diagnosis and judicious empiric antimicrobial management are, therefore, important to prevent further liver damage and decompensation. However, there is no consensus regarding the standard definition of post-KPE cholangitis, and established guidelines on evaluation and management are also lacking.
View Article and Find Full Text PDFspp. in neonatal sepsis: an urgent global threat.
Front Antibiot
September 2024
Institute of Infection & Immunity, St George's, University of London, London, United Kingdom.
Neonatal sepsis causes substantial morbidity and mortality, the burden of which is carried by low-income countries (LICs). The emergence of multidrug-resistant pathogens in vulnerable neonatal populations poses an urgent threat to infant survival. spp.
View Article and Find Full Text PDFComparison of Multi-Drug Resistant Organisms Causing Early Ventilator-Associated Pneumonia in Three Geographically Distinct Trauma Intensive Care Units.
Surg Infect (Larchmt)
January 2025
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
It is unclear why differences in patient location change organisms causing ventilator-associated pneumonia (VAP). We investigated VAP organisms in three geographically separate trauma intensive care units (TICUs). A retrospective review of organisms causing VAP (bronchoalveolar lavage [BAL] performed ≤7 d after admission and growing ≥10 cfu/mL) in three geographically separate TICUs was conducted.
View Article and Find Full Text PDFIntroduction-Aim: Spontaneous bacterial peritonitis (SBP) is a common complication in cirrhotic patients and is associated with a high mortality rate. The aim of this study is to determine the epidemiological and bacteriological profile of spontaneous bacterial peritonitis, as well as antibiotic resistance among hospitalized patients at CHU Mohammed VI, in order to guide empirical antibiotic choices for better management. Methods: This is a prospective study conducted over a period of 12 months, from January to December 2023, focusing on all requests for bacteriological examination of ascitic fluid samples.
View Article and Find Full Text PDFImpact of order set implementation on appropriate treatment of community-acquired pneumonia (CAP).
Antimicrob Steward Healthc Epidemiol
January 2025
Ascension Borgess Hospital, Kalamazoo, MI, USA.
Objective: This study aimed to evaluate appropriate antimicrobial prescribing after implementing a pneumonia order set within a community teaching hospital.
Design: Retrospective chart review study.
Setting: 450-bed community teaching hospital.
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