Synchrotron X-ray induced acoustic imaging.

Sci Rep

Department of Electrical Engineering and Creative IT Engineering, Medical Device Innovation Center, Pohang University of Science and Technology, Pohang, Republic of Korea.

Published: February 2021

X-ray induced acoustic imaging (XAI) is an emerging biomedical imaging technique that can visualize X-ray absorption contrast at ultrasound resolution with less ionizing radiation exposure than conventional X-ray computed tomography. So far, medical linear accelerators or industrial portable X-ray tubes have been explored as X-ray excitation sources for XAI. Here, we demonstrate the first feasible synchrotron XAI (sXAI). The synchrotron generates X-rays, with a dominant energy of 4 to 30 keV, a pulse-width of 30 ps, a pulse-repetition period of 2 ns, and a bunch-repetition period of 940 ns. The X-ray induced acoustic (XA) signals are processed in the Fourier domain by matching the signal frequency with the bunch-repetition frequency. We successfully obtained two-dimensional XA images of various lead targets. This novel sXAI tool could complement conventional synchrotron applications.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893053PMC
http://dx.doi.org/10.1038/s41598-021-83604-3DOI Listing

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