Background: The objective of this study was to determine if there is an impact of surgical delay on 5-year overall survival (OS) from early stage colon cancer, and if so, to define how long surgery can safely be postponed.
Methods: Using the NCDB, we compared early (14-30 days) and delayed surgery (31-90 days) in patients with Stage I/II colon cancer. Outcomes included OS at five years and odds of death.
Results: Delayed resection conferred a decreased 5-year OS of 73.0% (95% CI, 72.6-73.4), compared to early resection 78.3% (95% CI, 77.9-78.8). When time to surgery was divided into one-week intervals, there was no difference in the odds of death with delay up to 35-41 days (6 weeks), but odds of death increased by 9% per week thereafter.
Conclusions: These data support that definitive resection for early stage colon cancer may be safely delayed up to 6 weeks.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723420 | PMC |
| http://dx.doi.org/10.1016/j.amjsurg.2020.11.048 | DOI Listing |
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