Background: The treatment of chronic pancreatitis requires a surgical approach in patients who are refractory to medical therapy. During surgical treatment, ductal decompression is required, but a pancreatectomy is necessary for some patients, such as those with severe stenosis of the pancreatic duct. Indeed, suboptimal procedures lead to recurrent pancreatitis. We used a laparoscopic hybrid approach for patients with severe stenosis of the pancreatic duct. In this report, we present the feasibility and outcomes of our approach.
Methods: We selected a laparoscopic approach for the distal pancreatectomy, which is relatively safe and the effect of reducing the length of the wound is substantial. We selected an open approach for the Frey procedure because complete ductal compression has a high risk for injury to the vessels posterior to the pancreas. We recorded the operative outcomes, postoperative complications, and recurrence of pancreatitis.
Results: We performed the laparoscopic hybrid approach on 3patients between January and December 2018. There were no major intraoperative complications (Clavien-Dindo classification IIIa or more) and the postoperative course was uneventful in all patients. There were no recurrences of pancreatitis and no postoperative pain in all patients in > 2 years of follow-up.
Conclusion: Our hybrid method with a focus on complete ductal compression with safety and minimal invasiveness might be the optimal approach for the surgical treatment of chronic pancreatitis that requires a pancreatectomy with the Frey procedure.
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http://dx.doi.org/10.1186/s12893-021-01096-4 | DOI Listing |
Sci Rep
January 2025
School of Mechanical Engineering, College of Engineering, University of Tehran, Tehran, Iran.
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January 2025
Department of Electronics and Communication Engineering, Panimalar Engineering College, Chennai, India.
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January 2025
Department of Chemistry, Faculty of Science, Taibah University, Al-Madinah Al-Munawarah 30002 Saudi Arabia. Electronic address:
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Beijing Key Laboratory of Farmland Soil Pollution Prevention and Remediation, Key Laboratory of Plant-Soil Interactions of the Ministry of Education, College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193, PR China. Electronic address:
A comprehensive understanding of cadmium (Cd) migration in soils near contaminated hotspots is crucial for optimizing remediation efforts and ensuring crop health. This study investigates agricultural soils from four sites in mining and sewage-irrigation areas, assessing the impact of inorganic and organic fertilizer application on soil Cd remobilization. Results revealed that fertilization, particularly with mineral phosphorus, disrupts soil stability, substantially increases short-term Cd mobility in vulnerable regions.
View Article and Find Full Text PDFTheor Appl Genet
January 2025
Université Paris-Saclay, INRAE, CNRS, AgroParisTech, GQE - Le Moulon, 91190, Gif-sur-Yvette, France.
Phenomic selection based on parental spectra can be used to predict GCA and SCA in a sparse factorial design. Prediction approaches such as genomic selection can be game changers in hybrid breeding. They allow predicting the genetic values of hybrids without the need for their physical production.
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