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We report the design, construction, and initial tests of a hyperpolariser to produce polarised Xe and He gas for medical imaging of the lung. The hyperpolariser uses the Spin-Exchange Optical Pumping method to polarise the nuclear spins of the isotopic gas. Batch mode operation was chosen for the design to produce polarised Xe and polarised He. Two-side pumping, electrical heating and a piston to transfer the polarised gas were some of the implemented techniques that are not commonly used in hyperpolariser designs. We have carried out magnetic resonance imaging experiments demonstrating that the He and Xe polarisation reached were sufficient for imaging, in particular for in vivo lung imaging using Xe. Further improvements to the hyperpolariser have also been discussed.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882919PMC
http://dx.doi.org/10.1016/j.mri.2021.02.010DOI Listing

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