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| http://dx.doi.org/10.1016/j.jdcr.2020.12.022 | DOI Listing |
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Fibroelastolytic papulosis: two cases of disease spectrum variants.
Dermatol Online J
August 2024
Department of Dermatology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, New York, New York, USA.
Fibroelastolytic papulosis (FEP) is an acquired cutaneous disorder of elastin that encompasses both white fibrous papulosis of the neck (WFPN) and pseudoxanthoma elasticum (PXE)-like papillary dermal elastolysis (PDE). Although FEP is a benign acquired disorder, it shares overlapping clinical features with pseudoxanthoma elasticum (PXE), a genetic disorder with systemic manifestations. We report two cases of FEP, including the WFPN and PXE-like PDE variants, in elderly women.
View Article and Find Full Text PDFA Single-Center Cross-Sectional Observational Study on Dermoscopy of Genital Mucosal Disorders in a Tertiary Care Center in Central India.
Indian Dermatol Online J
October 2024
Department of Dermatology and Venereology, AIIMS, Habibganj, Saketnagar, Bhopal, Madhya Pradesh India.
Introduction: Dermoscopy of mucosa is known as mucoscopy. Mucoscopy can aid in delineating minute aspects of mucosal lesions and will guide in the differentiation of similar-looking lesions. To date, there are only a few studies on mucoscopy of genital dermatoses especially from India.
View Article and Find Full Text PDFRelationship Between Cytokines and Face Skin Symptoms in Newborns in Two Japanese Cities.
Skin Res Technol
October 2024
Department of Midwifery and Women's Health, Division of Health Sciences and Nursing, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Article Synopsis
- The study aimed to investigate how skin cytokine levels relate to various skin symptoms in newborns, addressing common inflammatory responses.
- Conducted in Tokyo and Oita, Japan, the research involved 231 healthy 1-month-old infants, evaluating symptoms like erythema and papules while measuring cytokine levels using skin blotting.
- Results indicated a significant link between the presence of papules and elevated IL-8 levels, suggesting different cytokines may contribute to varying skin conditions, which could inform future prevention strategies.
Treatment of skin lesions related to pseudoxanthoma elasticum in plastic surgery.
Ann Chir Plast Esthet
September 2024
Plastic surgery Unit, National Reference Center for PXE (MAGEC Nord), Department of Dermatology, 4, rue Larrey, 49933 Angers, France. Electronic address:
Article Synopsis
- Pseudoxanthoma elasticum (PXE) is a genetic connective tissue disorder that leads to skin changes, primarily yellow papules and excess skin around areas like the neck, causing notable aesthetic and psychological effects, especially in women.* -
- A study conducted at a University-Hospital from 2007 to 2022 evaluated treatment options for patients with PXE, focusing on surgical procedures to reduce the size of skin lesions rather than complete removal.* -
- Out of 250 patients, 30 underwent surgery with methods like facelifts and skin tightening; results were mostly satisfactory with no complications, highlighting the potential for effective surgical intervention in managing PXE-related skin issues.*
A Systematic Review of Clinical Features and Treatment Outcomes of Xanthoma Disseminatum.
J Cutan Med Surg
November 2024
Toronto Dermatology Centre, North York, ON, Canada.
Article Synopsis
- Xanthoma disseminatum (XD) is a rare skin condition within the group of non-Langerhans histiocytosis, presenting mainly as yellow-to-brown lesions on the face, flexures, trunk, and genital areas, and often associated with systemic issues.
- A comprehensive review of 151 studies revealed a total of 166 cases, predominantly in females with an average diagnosis age of 35.3 years, indicating the condition's extensive extracutaneous manifestations, including those affecting the pituitary gland and oropharynx.
- Despite various treatment options explored, including cladribine, systemic steroids, and others, there are low complete response rates, highlighting the need for further research to improve management strategies for
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