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http://dx.doi.org/10.5114/aic.2020.102134 | DOI Listing |
Proc Natl Acad Sci U S A
January 2025
Center for Ultrafast Science and Technology, School of Chemistry and Chemical Engineering, Zhang Jiang Institute for Advanced Study, Shanghai Jiao Tong University, Shanghai 200240, China.
Class II photolyases (PLs) are a distant subclade in the photolyase/cryptochrome superfamily, displaying a unique Trp-Tyr tetrad for photoreduction and exhibiting a lower quantum yield (QY) of DNA repair (49%) than class I photolyases (82%) [M. Zhang, L. Wang, S.
View Article and Find Full Text PDFSci Rep
December 2024
Canada Centre for Remote Sensing, Canada Centre for Mapping and Earth Observation, Natural Resources Canada, 580 Booth Street, Ottawa, ON, K1A 0E4, Canada.
Permafrost ground temperature and its spatial distribution are usually calculated using one-dimensional models based on heat flow in the vertical direction. Here, we theoretically calculated the impacts of lateral conductive heat flow on ground temperature under equilibrium and transient conditions. The results show that lateral heat flow has strong impacts on ground temperature, especially in deep ground.
View Article and Find Full Text PDFFront Immunol
December 2024
Myeloid Therapeutics, Inc., Cambridge, MA, United States.
Introduction: The approval of chimeric antigen receptor (CAR) T cell therapies for the treatment of B cell malignancies has fueled the development of numerous cell therapies. However, these cell therapies are complex and costly, and unlike in hematological malignancies, outcomes with most T cell therapies in solid tumors have been disappointing. Here, we present a novel approach to directly program myeloid cells by administering novel TROP2 CAR mRNA encapsulated in lipid nanoparticles (LNPs).
View Article and Find Full Text PDFStem Cells Int
December 2024
State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Clinical Research Center for Oral Diseases, Department of Orthodontics, School of Stomatology, The Fourth Military Medical University, No. 169 Changle West Road, Xi'an 710032, China.
Transient receptor potential ankyrin 1 (TRPA1) molecule is an important type of transient receptor potential (TRP) cation channels, which can cause extracellular Ca to flow into cells after activation. TRPA1 plays an important role in acute and chronic pain, inflammation, kidney disease, cough and asthma, osteoarthritis, cardiovascular disease, obesity, diabetes, and other diseases. In this study, the expression of interleukin (IL)-1, IL-6, and IL-8 in periodontal ligament stem cells (PDLSCs) treated by lipopolysaccharide (LPS) and the effect of LPS on PDLSCS proliferation were detected.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Theoretical Electrical Engineering and Diagnostics of Electrical Equipment, Institute of Electrodynamics, National Academy of Sciences of Ukraine, Beresteyskiy, 56, Kyiv-57, 03680, Ukraine.
Microgrids (MGs) have gained significant attention over the past two decades due to their advantages in service reliability, easy integration of renewable energy sources, high efficiency, and enhanced power quality. In India, low-voltage side customers face significant challenges in terms of power supply continuity and voltage regulation. This paper presents a novel approach for optimal power scheduling in a microgrid, aiming to provide uninterrupted power supply with improved voltage regulation (VR).
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