Aim: To evaluate Platelet-to-Lymphocyte Ratio (PLR) and Neutrophil-to-Lymphocyte Ratio (NLR) in patients with HP.
Method: A sample of 140 total patients, 50 having chronic HP and 20 having acute HP, and a control group of 70 more patients were included in this retrospective study conducted with hospital Ethical Committee approval.
Results: PLR and NLR values were significantly higher in all HP patients than in the control group ( p <0.001). In addition, these biomarkers were significantly higher in patients with acute HP than in the chronic HP group (p = 0.017 and p = 0.044, respectively). The cutoff values for PLR and NLR were: (1) 177 (p = 0.020) and 2.76 (p <0.0001) between the HP patients and the control group, and, (2) 110 (p = 0.0054) and 2.15 (p = 0.03), between the acute and chronic HP groups.
Conclusion: PLR and NLR values are inexpensive and easy parameters that can guide in diagnosing hypersensitivity pneumonia in combination with clinical, radiological and pathology findings.and the acute-chronic differentiation of the disease. .
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883515 | PMC |
| http://dx.doi.org/10.36141/svdld.v37i4.9966 | DOI Listing |
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Article Synopsis
- The study investigated the role of inflammation-related biomarkers (SII, SIRI, NLR, PLR) in predicting mid-term mortality and restenosis in patients with peripheral artery disease (PAD).
- During an average follow-up of about 21 months, researchers found that higher levels of these biomarkers correlated with increased mortality rates, particularly highlighting NLR as a significant independent risk factor.
- However, no significant links were established between these biomarkers and the occurrence of restenosis in the study participants.
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