Diagnosis of melioidosis: the role of molecular techniques.

Future Microbiol

University of Queensland Centre for Clinical Research, Royal Brisbane and Woman's Hospital, Herston, Queensland, 4029, Australia.

Published: March 2021

Melioidosis is an emerging infectious disease with an estimated global burden of 4.64 million disability-adjusted life years per year. A major determinant related to poor disease outcomes is delay to diagnosis due to the fact that identification of the causative agent may be challenging. Over the last 25 years, advances in molecular diagnostic techniques have resulted in the potential for rapid and accurate organism detection and identification direct from clinical samples. While these methods are not yet routine in clinical practice, laboratory diagnosis of infectious diseases is transitioning to culture-independent techniques. This review article aims to evaluate molecular methods for melioidosis diagnosis direct from clinical samples and discuss current and future utility and limitations.

Download full-text PDF

Source
http://dx.doi.org/10.2217/fmb-2020-0202DOI Listing

Publication Analysis

Top Keywords

direct clinical
8
clinical samples
8
diagnosis
4
diagnosis melioidosis
4
melioidosis role
4
role molecular
4
molecular techniques
4
techniques melioidosis
4
melioidosis emerging
4
emerging infectious
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!