AI Article Synopsis
- - A new assay called the transcription-reverse transcription concerted reaction (TRC) can detect influenza A and B in just 15 minutes using nasopharyngeal swabs and gargle samples from patients with influenza-like symptoms.
- - During studies conducted from January to March in both 2018 and 2019, TRC demonstrated perfect sensitivity and specificity (1.000) in nasal swabs, while in gargle samples, it showed sensitivity of 0.946 and perfect specificity (1.000).
- - The performance of the TRC assay is comparable to traditional RT-PCR methods for detecting influenza viruses, making it a promising rapid testing option.
Article Abstract
We evaluated a novel transcription-reverse transcription concerted reaction (TRC) assay that can detect influenza A and B within 15 min using nasopharyngeal swab and gargle samples obtained from patients with influenza-like illness, between January and March 2018 and between January and March 2019. Based on the combined RT-PCR and sequencing results, in the nasal swabs, the sensitivity and specificity of TRC for detecting influenza were calculated as 1.000 and 1.000, respectively. In the gargle samples, the sensitivity and specificity of TRC were 0.946 and 1.000, respectively. The TRC assay showed comparable performance to RT-PCR in the detection of influenza viruses.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7885976 | PMC |
| http://dx.doi.org/10.1007/s10096-021-04193-7 | DOI Listing |
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