Resting systolic and diastolic blood pressures were measured in age-matched bodybuilders (n = 31) and medical students (n = 37). Also, systolic blood pressure and heart rate were assessed during progressive cycle ergometer exercise at 100-200 W. Systolic and diastolic blood pressures at rest and systolic blood pressure response during exercise were comparable in bodybuilders and students. Bodybuilders, however, displayed lower (p less than 0.01-0.001) heart rate at identical power outputs of exercise. Consequently, when considering intergroup differences in muscle mass, circulatory responses were similar in bodybuilders and students. The results of the present study together with other observations suggest that intense long-term strength training, as performed by bodybuilders, does not constitute a potential cardiovascular risk factor.
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Biochem Biophys Res Commun
January 2025
Department of Ultrasonography, Fuwai Yunnan Hospital, Chinese Academy of Medical, Sciences/Affiliated Cardiovascular Hospital of Kunming Medical University, Kunming, 650102, China. Electronic address:
Pulmonary arterial hypertension (PAH) is a syndrome characterized by increased pulmonary vascular resistance and elevated pulmonary artery pressure, ultimately leading to right heart failure and even death. Increasing evidence implicates the fat mass and obesity-associated protein (FTO) in various metabolic and inflammatory pathways; however, its role in pulmonary endothelial function and PAH remains largely unexplored. In this study, we examined the effects of endothelial cell-specific FTO knockout on PAH development.
View Article and Find Full Text PDFAnn Intern Med
January 2025
Department of Epidemiology and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore; and Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland (T.M.B.).
Background: Guidelines emphasize quiet settings for blood pressure (BP) measurement.
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Design: Randomized crossover trial of adults in Baltimore, Maryland.
J Neurosurg Case Lessons
January 2025
The Trauma and Neuroscience Institutes, St. John's Hospital and Medical Center, Tulsa, Oklahoma.
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View Article and Find Full Text PDFAppl Physiol Nutr Metab
January 2025
University of Saskatchewan, Saskatoon, Saskatchewan, Canada;
We compared stretching, isometrics, and aerobic exercise for effectiveness in decreasing blood pressure post-exercise. Using a randomized crossover design, 5 males and 4 females (21.3y; normotensive) participated in four 30-minute sessions on separate days: static stretching (30s stretches, major muscle groups), isometric exercise, aerobic cycling (75% VO2peak), and control (rest), with blood pressure and heart rate measured before exercise (or rest) and for 60 minutes post-exercise (or rest).
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