AI Article Synopsis
- Adenomyoepithelioma (AME) is a rare tumor composed of both epithelial and myoepithelial cells, mainly benign but can progress to malignancy; this report focuses on a case of low-grade malignant AME to explore its features.
- A 64-year-old woman presented with a painless 4.5 cm mass in her left breast, which was diagnosed as malignant AME after histological examination.
- The treatment involved local excision, followed by mastectomy and sentinel lymph node biopsy, with one year of follow-up showing no signs of relapse; however, treatment for AME remains unclear due to limited data.
Article Abstract
Rationale: Adenomyoepithelioma (AME) is a rare biphasic tumor consisting of epithelial and Myoepithelial cell. Most of the AME is benign, and only a few will progress to malignancy, Here, we report a case of low-grade malignant adenomyoepithelioma, and review the related literature, in a bid to investigate its clinical and pathological features and thus, enhance our understanding of this tumor.
Patient Concerns: A 64-year-old woman visited our hospital with a 1-year history of a painless mass in her left breast. Physical examination revealed a palpable painless mass, measuring approximately 4.5 cm, in the left breast.
Diagnosis: Histological examination confirmed the diagnosis of malignant adenomyoepithelioma.
Interventions: The patient underwent local excision of the mass, with frozen section analysis revealing ductal carcinoma in situ. Mastectomy and sentinel lymph node biopsy were then performed.
Outcomes: We conducted a one-year follow-up, and relapse was not observed.
Lessons: Treatment of AME remains controversial owing to the lack of high volume data and absence of prospective studies. Simple mastectomy is an acceptable treatment of this tumor.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870234 | PMC |
| http://dx.doi.org/10.1097/MD.0000000000024461 | DOI Listing |
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