Macroscopic T-wave alternans (TWA) is the beat-to-beat variation in the amplitude or shape of the T wave on a surface electrocardiogram (ECG) and known to be a harbinger of impending malignant ventricular arrhythmias such as polymorphic ventricular tachycardia. We herein report a case with hepatic encephalopathy, who developed TWA, followed by polymorphic ventricular tachycardia.
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http://dx.doi.org/10.1016/j.jelectrocard.2021.01.011 | DOI Listing |
Circ Arrhythm Electrophysiol
October 2024
Gifu University Hospital (N.T., S.E., R.T., A.Y., T.W., T.K., Y.Y., H.K., H.U., H.O.).
Background: Little is known about the role of atrial arrhythmias (AAs) in triggering Torsade de Pointes (TdP) in patients with long QT syndrome (LQTS). The aim of this study was to examine the contribution of AAs to the development of TdP in acquired LQTS patients.
Methods: The initiation patterns of 81 episodes of TdP obtained from 34 consecutive acute acquired LQTS patients (14 men, median age, 69 years; median QTc, 645.
Rev Cardiovasc Med
September 2023
Department of Cardiology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, 264000 Yantai, Shandong, China.
The spiked helmet sign (SHS) is a rare electrocardiographic marker associated with an increased risk of lethal ventricular tachyarrhythmias and sudden cardiac death. To our knowledge, this is the first study aimed at reviewing recent research progress on this electrocardiogram (ECG) pattern to summarize its electrophysiological mechanisms, epidemiological features, clinical characteristics, and clinical significance. SHS formation is attributed to sympathetic hyperactivity, which mediates increased dispersion of ventricular repolarization, leading to marked QT prolongation and macroscopic T-wave alternans.
View Article and Find Full Text PDFChaos
April 2024
Department of Physics, and Institute of Theoretical and Computational Physics, University of Crete, Heraklion 70013, Greece.
The heart beats are due to the synchronized contraction of cardiomyocytes triggered by a periodic sequence of electrical signals called action potentials, which originate in the sinoatrial node and spread through the heart's electrical system. A large body of work is devoted to modeling the propagation of the action potential and to reproducing reliably its shape and duration. Connection of computational modeling of cells to macroscopic phenomenological curves such as the electrocardiogram has been also intense, due to its clinical importance in analyzing cardiovascular diseases.
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March 2024
National Reference Center for Inherited Arrhythmias of Lyon, Department of Cardiac Electrophysiology, Louis Pradel Hospital, Hospices Civils de Lyon, Lyon, France; University of Lyon, Claude Bernard Lyon 1 University, MeLiS, CNRS UMR 5284, INSERM U1314, Institut NeuroMyoGène, Lyon 69008, France. Electronic address:
Eur Heart J Case Rep
November 2023
Department of Cardiology, Mater Dei Hospital, Triq Dun Karm, Birkirkara, Msida, MSD 2090, Malta.
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