Successful management of donor-acquired fat embolism after lung transplantation.

Interact Cardiovasc Thorac Surg

Department of Thoracic Surgery and Lung Transplantation, Foch Hospital, Suresnes, France.

Published: June 2021

Fat embolism is a serious complication in patients with multiple traumatic injuries. It is often asymptomatic during the first hours of resuscitation, thus remains underdiagnosed in patients who progress to brain death. Lung transplantation issued from such grafts can lead to severe lung primary graft dysfunction, the management of which is deemed difficult. Herein, we report a successful management of donor-acquired fat embolism syndrome after lung transplant in a 22 years old woman for cystic fibrosis. Fat embolism was suspected because of the donor's traumatic injuries and confirmed by histopathological analysis. An immediate postoperative primary graft dysfunction was successfully managed with veno-arterial extracorporeal membrane oxygenation. The patient is alive 31 months after surgery.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923421PMC
http://dx.doi.org/10.1093/icvts/ivab051DOI Listing

Publication Analysis

Top Keywords

fat embolism
16
successful management
8
management donor-acquired
8
donor-acquired fat
8
lung transplantation
8
traumatic injuries
8
primary graft
8
graft dysfunction
8
fat
4
embolism
4

Similar Publications

Background: Autologous fat grafting in the buttocks has gained great popularity However, one of the main risks is infiltration of fat into the systemic venous system, leading to potential complications such as macroscopic fatty embolism (MAFE), which can be fatal.

Objectives: This study evaluated the safety and efficacy of the LiRi (Linear Retrograde infiltration) for autologous fat grafting in the buttocks, and its evolution over a six-month follow-up period.

Methods: The procedure was performed in 114 patients.

View Article and Find Full Text PDF
Article Synopsis
  • The study explored how extracellular histone H4 contributes to acute respiratory distress syndrome (ARDS) triggered by oleic acid (OA) in mice.
  • The research found that levels of histone H4 increased significantly after OA injection, correlating with the severity of ARDS, and that pre-treatment with histone H4 worsened lung edema and mortality.
  • Histone H4 activated endothelial cells through mechanisms involving heparan sulfate degradation and certain receptors, leading to inflammation and thrombus formation in the lungs.
View Article and Find Full Text PDF

Background: Autologous fat transplantation has gained increasing attention in the field of cosmetic surgery. However, a series of complications can occur after fat transplantation.

Case Presentation: A 24-year-old woman presented at our Hospital with nasal skin necrosis and ulceration.

View Article and Find Full Text PDF

A 74-year-old woman presented with sudden dyspnea 22 h after orthopedic surgery. Echocardiography revealed significant right ventricular dilatation, suggesting the development of acute pulmonary embolism. However, contrast computed tomography showed no signs of pulmonary thromboembolism, leading to suspicion of fat embolism syndrome (FES).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!