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Immersive virtual reality (VR) environments are a powerful tool to explore cognitive processes ranging from memory and navigation to visual processing and decision making-and to do so in a naturalistic yet controlled setting. As such, they have been employed across different species, and by a diverse range of research groups. Unfortunately, designing and implementing behavioral tasks in such environments often proves complicated.
View Article and Find Full Text PDFIntrinsic timing of brood care in shell-dwelling cichlids.
Curr Biol
January 2025
Max Planck Institute for Biological Intelligence, 82152 Martinsried, Germany. Electronic address:
Brood care relies on interactions between parents and offspring. Emergence of nestlings from their nest has been hypothesized to rely on the readout by the parent of the maturational state of the young. Theoretical considerations predict a conflict: parents should push for early emergence, if possible, to reduce care demands and maximize the number of reproductive cycles, whereas offspring should delay leaving to maximize resource allocation and protection by the parents.
View Article and Find Full Text PDFStudying power-grid synchronization with incremental refinement of model heterogeneity.
Chaos
January 2025
Institute of Technical Physics and Materials Science, HUN-REN Centre for Energy Research, P.O. Box 49, H-1525 Budapest, Hungary.
The dynamics of electric power systems are widely studied through the phase synchronization of oscillators, typically with the use of the Kuramoto equation. While there are numerous well-known order parameters to characterize these dynamics, shortcoming of these metrics are also recognized. To capture all transitions from phase disordered states over phase locking to fully synchronized systems, new metrics were proposed and demonstrated on homogeneous models.
View Article and Find Full Text PDFCurative-Intended Management of Synchronous Esophageal and Rectal Cancer-A Systematic Literature Review.
J Gastrointest Cancer
January 2025
Department of Radiotherapy and Radiation Oncology, Jena University Hospital, 07747, Jena, Germany.
Purpose: Synchronous esophageal (EC) and rectal carcinoma (RC) is a rare and challenging condition, particularly in curative-intended treatment. Especially locally advanced tumors may not be suitable for primary resection and require individual multimodal treatment. This review examines curative-intended management of synchronous EC and RC.
View Article and Find Full Text PDFSurpassing protein specificity in biomimetics of bacterial amyloids.
Int J Biol Macromol
January 2025
Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina, Instituto de Salud Carlos III, Barcelona, Spain; Departament de Genètica i de Microbiologia, Universitat Autònoma de Barcelona, Barcelona, Spain; Institut de Recerca Sant Pau (IR SANT PAU), 08041 Barcelona, Spain. Electronic address:
In nature, nontoxic protein amyloids serve as dynamic, protein-specific depots, exemplified by both bacterial inclusion bodies and secretory granules from the endocrine system. Inspired by these systems, chemically defined and regulatory-compliant artificial protein microgranules have been developed for clinical applications as endocrine-like protein repositories. This has been achieved by exploiting the reversible coordination between histidine residues and divalent cations such as Zn, that promotes protein-protein interactions.
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