[Treatment-refractory anaemia in a 35-year-old heart transplant recipient on chronic hemodialysis].

Internist (Berl)

Klinik für Nieren- und Hochdruckerkrankungen, Medizinische Hochschule Hannover, Carl-Neuberg-Straße 1, 30625, Hannover, Deutschland.

Published: July 2021

This article presents a case of pure red cell aplasia in a 35-year-old heart transplant recipient on chronic hemodialysis. Elevated parvovirus B19 immunoglobulin M blood levels were detected along with a high viral load of 80 billion IU/ml quantified by polymerase chain reaction. Bone marrow examination revealed giant proerythroblasts confirming parvovirus B19 infection. High-dose intravenous immunoglobulin was used for treatment. Anaemia had significantly improved 4 weeks later. Parvovirus B19 infection should be excluded in organ transplant recipients with anaemia due to ineffective erythropoiesis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8260535PMC
http://dx.doi.org/10.1007/s00108-021-00955-9DOI Listing

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