Failure of rapamycin to extend lifespan in DNA repair mutant and telomerase-knockout mice, while extending lifespan in normal mice, indicates that neither DNA damage nor telomere shortening limits normal lifespan or causes normal aging.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906135PMC
http://dx.doi.org/10.18632/aging.202674DOI Listing

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