AI Article Synopsis
- A study involving 250 women evaluated the effectiveness of various doses of oral tilidine (25, 50, and 100 mg) for postepisiotomy pain compared to oral pentazocine (50 mg).
- All doses of tilidine and pentazocine provided significant pain relief, with tilidine 50 mg performing similarly to pentazocine; however, none of the comparisons were statistically significant.
- Tilidine 25 mg was effective with minimal side effects, while tilidine 100 mg and pentazocine 50 mg had a 25% incidence of side effects, mostly dizziness and drowsiness.
Article Abstract
A controlled, double-blind study involving 250 women was carried out ot assess the efficacy of oral tilidine 25, 50 and 100 mg in treating postepisiotomy pain, and to offer a comparison with oral pentazocine 50 mg. All the analgesics produced significant pain relief. At peak effect tilidine 50 mg produced very similar results to pentazocine 50 mg with tilidine 25 mg producing less, and tilidine 100 mg more pain relief. These results were not, however, statistically significant. In these postdelivery ambulant patients pentazocine 50 mg and tilidine 100 mg produced at 25% incidence of side-effects, mainly dizziness and drowsiness, but tilidine 25 mg produced significant analgesia with virtually no side-effects.
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