AI Article Synopsis
- This study tested the effectiveness of combining dexmedetomidine with lidocaine for pain control in patients undergoing impacted third molar extractions compared to using lidocaine alone.
- Patients were randomly assigned to receive either just lidocaine or lidocaine with dexmedetomidine, and their pain levels were measured at various times after surgery.
- Results showed that the group receiving the combination experienced significantly lower pain scores during and after the procedure, suggesting that dexmedetomidine improves pain management in dental surgeries.
Article Abstract
Objectives: Administration of medications such as dexmedetomidine as a topical anesthetic has been suggested in the pain control in dentistry. This double-blind randomized control trial study evaluated postoperative pain and associated factors following impacted third molar extraction surgery. Lidocaine alone was taken as the control and lidocaine plus dexmedetomidine as the intervention.
Materials And Methods: Forty patients undergoing mandibular third molar extraction entered the study and were randomly allocated to the control and interventional groups. 0.15 ml of dexmedetomidine was added to each lidocaine cartridge and the drug concentration was adjusted to 15 g for the intervention group while only lidocaine was used in the control group. A visual analog scale was used to measure and record pain levels at the end of the surgery and 6, 12, and 24 hours after the surgery and number of painkillers taken by the patients after the surgery was also recorded.
Results: Pain scores of the intervention group decreased significantly during the surgery and also 6, 12, and 24 hours after the surgery compared to the control group. The pain score was correlated significantly with our intervention during the surgery and also 6 and 12 hours after that (all value < 0.05). There was a nonsignificant reduction in the number of painkillers taken by the patients at 6, 12, and 24 hours after surgery (all value > 0.05).
Conclusion: In patients undergoing molar surgery, administration of a combination of dexmedetomidine and lidocaine is beneficial for the pain control. Compared to the injection of lidocaine alone, combination of dexmedetomidine and lidocaine can be used for a better pain control in molar surgeries.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857915 | PMC |
| http://dx.doi.org/10.1155/2021/6623792 | DOI Listing |
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