AI Article Synopsis
- * PGP-I-I is primarily composed of 1,5-α-L-arabinan, and includes arabinogalactan chains linked to a rhamnogalacturonan I backbone, which is further connected to longer galacturonan chains.
- * In vitro studies indicate that PGP-I-I enhances intestinal cellular antioxidant defenses under hydrogen peroxide stress by increasing the expression of antioxidant genes, thereby mitigating oxidative damage.
Article Abstract
Platycodonis Radix is widely used as homology of medicine and food in China; polysaccharides are thought to be one of its functional constituents. In this study, a pectic polysaccharide, PGP-I-I, was obtained from the root of the traditional medicine plant Platycodon grandiflorus through ion exchange chromatography and gel filtration. This was characterized being mainly composed of 1,5-α-L-arabinan and both arabinogalactan type I (AG-I) and II chains linked to rhamnogalacturonan I (RG-I) backbone linked to longer galacturonan chains. In vitro bioactivity study showed that PGP-I-I could restore the intestinal cellular antioxidant defense under the condition of hydrogen peroxide (HO) treatment through promoting the expressions of cellular antioxidant genes and protect against oxidative damages.
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| http://dx.doi.org/10.1016/j.ijbiomac.2021.02.041 | DOI Listing |
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