Metabolomic and secretomic analyses of Aspergillus niger IOC 4687 indicated the features of resistance of this strain to copper stress. To investigate the metabolites produced under oxidative stress conditions, gas chromatography-mass spectrometry analysis was performed. The secretome principal component analysis results showed that mannitol could be the main metabolite responsible for conferring resistance to the fungus, and gluconic acid is the possible cause of copper desorption because of its chelating ability. The meta-analysis of the metabolome of A. niger IOC 4687 indicated that a low concentration of sorbitol and ribonolactone during growth may be an indicator of oxidative stress.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/mtomcs/mfaa010 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A New Species of Unibarra (Monogenoidea, Dactylogyridae) Parasite of Oxydoras niger From Juruá River, State of Acre, Brazil and New Data for U. paranoplatensis.
Acta Parasitol
June 2023
Laboratório de Helmintos Parasitos de Peixes, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz - Fiocruz, Avenida Brasil, 4365, Rio de Janeiro, RJ, 21040-900, Brasil.
Monogenoids are ectoparasites that have a simple one-host lifecycle, high species diversity, and a relatively high host specificity. During studies on the helminth fauna of fishes from the Jurua River, in Acre State, Brazil, a new species of the monotypic genus Unibarra Suriano & Incorvaia, 1995 was found parasitizing Oxydoras niger Valenciennes, 1821. Unibarra juruaensis n.
View Article and Find Full Text PDFMetabolomic and secretomic approach to the resistance features of the fungus Aspergillus niger IOC 4687 to copper stress.
Metallomics
January 2021
Dempster MS Lab, Chemical Engineering Department of Polytechnic School of University of São Paulo, Rua do Lago 250, Bloco B 3 andar, 05508-080 São Paulo-SP, Brasil.
Metabolomic and secretomic analyses of Aspergillus niger IOC 4687 indicated the features of resistance of this strain to copper stress. To investigate the metabolites produced under oxidative stress conditions, gas chromatography-mass spectrometry analysis was performed. The secretome principal component analysis results showed that mannitol could be the main metabolite responsible for conferring resistance to the fungus, and gluconic acid is the possible cause of copper desorption because of its chelating ability.
View Article and Find Full Text PDFResponse mechanism of mine-isolated fungus Aspergillus niger IOC 4687 to copper stress determined by proteomics.
Metallomics
September 2019
Dempster MS Lab - Chemical Engineering Department of Polytechnic School of University of São Paulo, Rua do Lago, 250, Bloco B 3 andar, São Paulo-SP, 05508-080, Brazil.
Proteomic analysis of the fungus Aspergillus niger showed that its capacity to absorb metals was boosted by physiological modification under metal stress conditions. To investigate the proteome elicited by copper stress, the mine-isolated strain A. niger IOC 4687 was cultured in the absence (control) or presence of copper ions (50 mg L) for 72 h.
View Article and Find Full Text PDFDesign of an enzyme cocktail consisting of different fungal platforms for efficient hydrolysis of sugarcane bagasse: Optimization and synergism studies.
Biotechnol Prog
September 2016
Laboratórios de Desenvolvimento de Bioprocessos, Departamento de Engenharia Bioquímica, Escola de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21949-900, Brazil.
Lignocellulosic materials represent a very important and promising source of renewable biomass. In order to turn them into fermentable sugars, synergism among the different enzymes that carry out bioconversion of these materials is one of the main factors that should be considered. Experimental mixture design was performed to optimize the proportion of enzymes produced by native strains of Trichoderma harzianum IOC 3844, Penicillium funiculosum ATCC 11797, and Aspergillus niger ATCC 1004, resulting in a proportion of 15, 50, and 35%, respectively.
View Article and Find Full Text PDFRecombinant Trichoderma harzianum endoglucanase I (Cel7B) is a highly acidic and promiscuous carbohydrate-active enzyme.
Appl Microbiol Biotechnol
November 2015
Departamento de Física e Informática, Instituto de Física de São Carlos, Universidade de São Paulo, Av. Trabalhador Sãocarlense, 400, São Carlos, SP, 13566-590, Brazil.
Trichoderma filamentous fungi have been investigated due to their ability to secrete cellulases which find various biotechnological applications such as biomass hydrolysis and cellulosic ethanol production. Previous studies demonstrated that Trichoderma harzianum IOC-3844 has a high degree of cellulolytic activity and potential for biomass hydrolysis. However, enzymatic, biochemical, and structural studies of cellulases from T.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!