Patients with schizophrenia have altered visual cognition and retinal functions. No studies have explored if retinal anomalies are related to visual cognition and the presence of visual hallucinations (VH). We explored functional responses of the retinal ganglion cells in schizophrenia patients with or without VH and conducted a neuropsychological evaluation to explore the links between cognition and retinal function. The VH+ group showed poorer visual cognition and we found correlations between the amplitudes of the P50 and the N95 waves and visual cognition. Our results provide arguments for a link between retinal dysfunction, impaired visual processing and VH in schizophrenia.
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http://dx.doi.org/10.1016/j.psychres.2021.113780 | DOI Listing |
Commun Biol
December 2024
Brain and Cognition, Faculty of Psychology and Educational Sciences, KU Leuven, Leuven, Belgium.
The functional organization of the human object vision pathway distinguishes between animate and inanimate objects. To understand animacy perception, we explore the case of zoomorphic objects resembling animals. While the perception of these objects as animal-like seems obvious to humans, such "Animal bias" is a striking discrepancy between the human brain and deep neural networks (DNNs).
View Article and Find Full Text PDFJ Affect Disord
December 2024
Department of Psychiatry, University of Muenster, Germany; Department of Psychiatry, University of Melbourne, Melbourne, Australia; The Florey Institute of Neuroscience and Mental Health, Melbourne, Australia.
Background: Cognitive dysfunction is a symptom of depression (MDD). While the involvement of the immune system has long been suggested to contribute to the biological underpinnings of depression, less is known about the underpinnings of cognitive dysfunction. A recent genome-wide association study pointed to genes related to immune function to be relevant for cognitive processes in depression.
View Article and Find Full Text PDFJ Sleep Res
December 2024
Department of Otorhinolaryngology, Radboud University Medical Center, Nijmegen, The Netherlands.
This study aimed to improve our understanding of sleep problems as a comorbidity of hereditary deaf-blindness due to Usher syndrome type 2a. Fifteen patients with Usher syndrome type 2a with a conclusive genetic diagnosis and 15 unaffected controls participated in comprehensive sleep and activity assessments for 2 weeks, using the MotionWatch 8 actigraph and consensus sleep diary. Various sleep parameters including sleep opportunity window, sleep latency, sleep efficiency, and self-reported sleep quality were analysed.
View Article and Find Full Text PDFPLoS One
December 2024
Machine Learning Group, Centrum Wiskunde & Informatica, Amsterdam, The Netherlands.
The acquisition of knowledge and skills does not occur in isolation but learning experiences amalgamate within and across domains. The process through which learning can accelerate over time is referred to as learning-to-learn or meta-learning. While meta-learning can be implemented in recurrent neural networks, these networks tend to be trained with architectures that are not easily interpretable or mappable to the brain and with learning rules that are biologically implausible.
View Article and Find Full Text PDFSci Rep
December 2024
School of Artificial Intelligence and Computer Science, Jiangnan University, Wuxi, 214122, China.
The unknown boundary issue, between superior computational capability of deep neural networks (DNNs) and human cognitive ability, has becoming crucial and foundational theoretical problem in AI evolution. Undoubtedly, DNN-empowered AI capability is increasingly surpassing human intelligence in handling general intelligent tasks. However, the absence of DNN's interpretability and recurrent erratic behavior remain incontrovertible facts.
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