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| http://dx.doi.org/10.36660/abc.20200715 | DOI Listing |
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Exercise Stress Testing Enhances Plasma Protein Carbonyl Levels in Patients With Asymptomatic Moderate-to-Severe Aortic Stenosis.
Oxid Med Cell Longev
December 2024
Department of Thromboembolic Disorders, Institute of Cardiology, Jagiellonian University Medical College, 80 Pradnicka St. 31-202, Krakow, Poland.
Exercise stress test-induced hypofibrinolysis and changes in circulating levels of several interleukins have been observed in aortic stenosis (AS). However, it is unknown whether the pattern of exercise-induced changes in oxidative stress differs between AS patients and controls and if the differences are associated with changes in fibrinolysis and inflammation. We studied 32 asymptomatic patients with moderate-to-severe AS and 32 controls of similar age, sex, and body mass index.
View Article and Find Full Text PDFAIHEMAF-P: An Innovative Healthcare Model for Atrial Fibrillation Patients.
Pharmacy (Basel)
December 2024
R&D for Clinical Activity in Telemedicine, Italian National Health Agency-AGENAS, 00187 Rome, Italy.
Atrial fibrillation (AF) is one of the most common cardiac arrhythmias of clinical relevance and a major cause of cardiovascular morbidity and mortality. Following a diagnosis of AF, patients are directed towards therapy with anticoagulant drugs to reduce the thromboembolic risk and antiarrhythmics to control their cardiac rhythm, with periodic follow-up checks. Despite the great ease of handling these drugs, we soon realized the need for follow-up models that would allow the appropriateness and safety of these pharmacological treatments to be monitored over time.
View Article and Find Full Text PDFIdentification of key factors related to digital health observational study adherence and retention by data-driven approaches: an exploratory secondary analysis of two prospective longitudinal studies.
Lancet Digit Health
January 2025
Biomedical Engineering Department, Duke University, Durham, NC, USA; Biostatistics and Bioinformatics Department, Duke University, Durham, NC, USA. Electronic address:
Background: Longitudinal digital health studies combine passively collected information from digital devices, such as commercial wearable devices, and actively contributed data, such as surveys, from participants. Although the use of smartphones and access to the internet supports the development of these studies, challenges exist in collecting representative data due to low adherence and retention. We aimed to identify key factors related to adherence and retention in digital health studies and develop a methodology to identify factors that are associated with and might affect study participant engagement.
View Article and Find Full Text PDF[Multidisciplinary and multiprofessional care to multimorbid chronic patients with cardiovascular disease: the experience of the Azienda Sanitaria Universitaria Giuliano Isontina].
G Ital Cardiol (Rome)
January 2025
S.C. Patologie Diabetiche, Dipartimento Specialistico Territoriale, Azienda Sanitaria Giuliano Isontina - Dipartimento Universitario Clinico di Scienze Mediche, Chirurgiche e della Salute, Università degli Studi, Trieste.
The world of chronic non-communicable diseases is progressively growing epidemiologically, requiring a significant commitment of resources, continuity of care, and strong integration between healthcare professionals and care settings. The National Recovery and Resilience Plan, in the Ministerial Decree 77 of 23/5/2022, identifies Community Homes as the privileged location for providing integrated, multidisciplinary and multiprofessional interventions, involving specialists and nursing clinics, general practitioners and district structures, utilizing all the necessary technological equipment, including digital platforms for telemedicine. In this context, cardiology is facing a complicated challenge: cardiologists must take care of patients with cardiovascular diseases who have also complex comorbidities and are required to extend their knowledge beyond the specific, sometimes super-specialistic, cardiovascular field, to avoid fragmentation, redundancy, and potential conflicts in the diagnostic-therapeutic care pathways.
View Article and Find Full Text PDFMethodological Challenges in Randomized Controlled Trials of mHealth Interventions: Cross-Sectional Survey Study and Consensus-Based Recommendations.
J Med Internet Res
December 2024
Institute for Complementary and Integrative Medicine, University of Zurich, Zurich, Switzerland.
Background: Mobile health (mHealth) refers to using mobile communication devices such as smartphones to support health, health care, and public health. mHealth interventions have their own nature and characteristics that distinguish them from traditional health care interventions, including drug interventions. Thus, randomized controlled trials (RCTs) of mHealth interventions present specific methodological challenges.
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