AI Article Synopsis
- Laser Doppler vibrometry (LDV) is the standard measurement technique for evaluating active middle ear implants (AMEI) using human temporal bones, essential during the implant's development and approval.
- The effectiveness of the AMEI is highly influenced by how well the floating mass transducer is coupled to the middle ear structures, which directly affects patient hearing experience.
- While forward stimulation has a defined ASTM standard for testing, a comparable standard for reverse stimulation is lacking, highlighting the need for improved preparation and testing protocols for human temporal bone to obtain reliable results.
Article Abstract
Laser Doppler vibrometric (LDV) measurements on human temporal bones represent the standard method for predicting the performance of active middle ear implants (AMEI) and are used as preclinical tests in the development, approval process, and indication expansion of AMEI. The quality of the coupling of the floating mass transducer to the mobile structures of the middle ear is decisive for the performance of the implant and patients' hearing perception. The cochlea can be stimulated via the oval window (forward stimulation) or the round window (reverse stimulation). For forward stimulation, the ASTM standard F2504-05 defines a method to ensure physiologically normal properties of the temporal bones used in the experiments. For reverse stimulation, which depends even more critically on the quality of the temporal bone, a comparable standard method is lacking. Appropriate preparation and storage of the human petrous bone as well as suitable LDV test setups with respect to calibration and reproducibility of measuring positions and angles provide results that allow a comparison of different types of coupling and also correlate well with clinical data.
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Article Synopsis
- Laser Doppler vibrometry (LDV) is the standard measurement technique for evaluating active middle ear implants (AMEI) using human temporal bones, essential during the implant's development and approval.
- The effectiveness of the AMEI is highly influenced by how well the floating mass transducer is coupled to the middle ear structures, which directly affects patient hearing experience.
- While forward stimulation has a defined ASTM standard for testing, a comparable standard for reverse stimulation is lacking, highlighting the need for improved preparation and testing protocols for human temporal bone to obtain reliable results.
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