New paulomycins produced by Streptomyces paulus.

J Antibiot (Tokyo)

Upjohn Company, Kalamazoo, Michigan 49001.

Published: February 1988

Paulomycin A2 (C34H46N2O17S), paulomycin C (C32H42N2O17S), paulomycin D (C31H40N2O17S), paulomycin E (C29H36N2O16S) and paulomycin F (C29H38N2O16S) have been isolated from fermentations of Streptomyces paulus strain 273. The structure of these compounds was determined using NMR and mass spectroscopic techniques. The new paulomycins, like paulomycins A and B (J. Antibiotics 35: 285-294, 1982) are highly active mainly against Gram-positive organisms.

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http://dx.doi.org/10.7164/antibiotics.41.157DOI Listing

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