AI Article Synopsis

  • Spinal cord injury (SCI) significantly affects patients' physical, psychological, and social aspects of life, leading to severe disability.
  • Advances in treatment over recent decades include improved understanding of injuries and strategies like pharmacological agents, surgery, and experimental neuroprotective methods, but many treatment areas remain controversial.
  • The lack of consensus on optimal care standards across treatment centers highlights the importance of updated approaches to early management to mitigate neurologic damage and reduce long-term disability.

Article Abstract

Spinal cord injury (SCI) is a debilitating condition which often leads to a severe disability and ultimately impact patient's physical, psychological, and social well-being. The management of acute SCI has evolved over the couple of decades due to improved understanding of injury mechanisms and increasing knowledge of disease. Currently, the early management of acute SCI patient includes pharmacological agents, surgical intervention and newly experimental neuroprotective strategies. However, many controversial areas are still surrounding in the current treatment strategies for acute SCI, including the optimal timing of surgical intervention, early versus delayed decompression outcome benefits, the use of methylprednisolone. Due to the lack of consensus, the optimal standard of care has been varied across treatment centres. The authors have shed a light on the current updates on early treatment approaches and neuroprotective strategies in the initial management of acute SCI in order to protect the early neurologic injury and reduce the future disability.

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Source
http://dx.doi.org/10.1515/revneuro-2020-0148DOI Listing

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