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| http://dx.doi.org/10.1007/s10815-021-02102-7 | DOI Listing |
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Microbiota analysis of perimenopausal women experiencing recurrent vaginitis in conjunction with urinary tract infection.
BMC Microbiol
January 2025
Shanghai-MOST Key Laboratory of Health and Disease Genomics, NHC Key Lab of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, 200237, China.
Background: Recurrent vaginitis in conjunction with urinary tract infection (RV/UTI) in perimenopausal women is a common clinical condition that impacts both doctors and patients. Its pathogenesis is not completely known, but the urogenital microbiota is thought to be involved. We compared the urogenital and gut microbiotas of perimenopausal women experiencing RV/UTI with those of age-matched controls to provide a new microbiological perspective and scheme for solving clinical problems.
View Article and Find Full Text PDFCordycepin affects Streptococcus mutans biofilm and interferes with its metabolism.
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January 2025
Academy of Medical Engineering and Transform Medicine, Tianjin University, No.92 Weijin Road, Nankai District, Tianjin, 300072, China.
Background: Streptococcus mutans (S. mutans) contributes to caries. The biofilm formed by S.
View Article and Find Full Text PDFEffects of culturally-appropriate group education for migrants with type 2 diabetes in primary healthcare: pre-test-post-test design.
BMC Prim Care
January 2025
Department of Public Health and Caring Sciences, Uppsala University, P O Box 564, Uppsala, S-751 22, Sweden.
Background: The global incidence of type 2 diabetes is rapidly rising, particularly among migrants in developed countries. Migrants bear a significant burden of diabetes. However, this study is the only to evaluate the effects of a culturally appropriate diabetes intervention for these migrants on diabetes knowledge and health outcomes, adding a novel perspective to the existing literature.
View Article and Find Full Text PDFAlternative healthcare delivery arrangements in Nepal: a systematic review of comparative effectiveness, safety and cost-effectiveness studies.
BMJ Glob Health
January 2025
School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia
Background: The way that healthcare services are organised and delivered (termed 'healthcare delivery arrangements') is a key aspect of a health system. Changing the way health care is delivered, for example, task shifting that delivers the same care at lower cost, may be one way of improving healthcare system sustainability. We synthesised the existing randomised trial evidence to compare the effects of alternative healthcare delivery arrangements versus usual care in Nepal.
View Article and Find Full Text PDFHigh-resolution dissection of human cell type-specific enhancers in cis and trans activities.
Genomics
January 2025
Center for Bioinformatics, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing 100871, PR China. Electronic address:
The spatiotemporal-specific gene expression is regulated by cell-type-specific regulatory elements. Here we selected the H3K4me1-associated DNA sequences as candidate enhancers in two different human cell lines and performed ChIP-STARR-seq to quantify the cell-type-specific enhancer activities with high-resolution. We investigated how the activity landscape of enhancer repository would change when transferred from native cells (cis activity) to another cell lines (trans activity).
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