Microbiomes: Infant Chimps Crawling with Bacteria.

Curr Biol

Department of Ecology and Evolutionary Biology, Cornell University, Ithaca, NY 14850, USA. Electronic address:

Published: February 2021

Human guts are colonized at birth by a limited set of microbes that gradually increases in diversity throughout infancy. A new study reports the opposite pattern in infant chimpanzees, raising questions about how host-microbiota relationships have changed during ape evolution.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010617PMC
http://dx.doi.org/10.1016/j.cub.2020.11.045DOI Listing

Publication Analysis

Top Keywords

microbiomes infant
4
infant chimps
4
chimps crawling
4
crawling bacteria
4
bacteria human
4
human guts
4
guts colonized
4
colonized birth
4
birth limited
4
limited set
4

Similar Publications

Aging is the main risk factor for developing cognitive impairments and associated neurodegenerative diseases. However environmental factors, including nutritional health, are likely to promote or reduce cognitive impairments and neurodegenerative pathologies. An intricate relationship exists between maternal nutrition; and adult eating behavior, metabolic phenotype and cognitive abilities.

View Article and Find Full Text PDF

Background: The human gut microbiota develops in concordance with its host over a lifetime, resulting in age-related shifts in community structure and metabolic function. Little is known about whether these changes impact the community's response to microbiome-targeted therapeutics. Providing critical information on this subject, faecal microbiomes of subjects from six age groups, spanning from infancy to 70-year-old adults (n = six per age group) were harvested.

View Article and Find Full Text PDF

Human milk oligosaccharides (HMOs), the third most abundant solid component in human milk, vary significantly among women due to factors such as secretor status, race, geography, season, maternal nutrition and weight, gestational age, and delivery method. In recent studies, HMOs have been shown to have a variety of functional roles in the development of infants. Because HMOs are not digested by infants, they act as metabolic substrates for certain bacteria, helping to establish the infant's gut microbiota.

View Article and Find Full Text PDF

Microbiome abnormalities (dysbiosis) significantly contribute to the progression of Alzheimer's disease (AD). However, the therapeutic efficacy of microbiome modulators in protecting against these ailments remains poorly studied. Herein, we tested a cocktail of unique probiotics, including 5 Lactobacillus and 5 Enterococcus strains isolated from infant gut with proven microbiome modulating capabilities.

View Article and Find Full Text PDF

Maternal pre- and postnatal stress and maternal and infant gut microbiota features.

Psychoneuroendocrinology

January 2025

Radboud university medical center, Donders Institute for Brain, Cognition and Behaviour, Department of Cognitive Neuroscience, Nijmegen, the Netherlands.

Background: Maternal stress can have short and long term adverse (mental) health effects for the mother and her child. Previous evidence suggests that the gut microbiota may be a potential mediator and moderator for the effects of stress via various pathways. This study explored the maternal microbiota trajectory during pregnancy as well as the association between pre- and postnatal maternal stress and features of the maternal and infant gut microbiota during and after pregnancy.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!