AI Article Synopsis

  • Older individuals commonly experience reduced peak expiratory flow (PEF), which can indicate a higher risk for sarcopenia, a condition marked by muscle loss.
  • The study analyzed data from 2,422 older Indonesians (aged ≥60) to investigate the link between PEF levels and sarcopenia, using measurements like handgrip strength and gait speed for diagnosis.
  • Results showed that lower PEF levels (<50% and 50%-80%) significantly increased the odds of sarcopenia, highlighting a strong connection between poor lung function and muscle deterioration in older adults.

Article Abstract

Reduced peak expiratory flow is a common physiological change in older individuals and age is an important predictor for sarcopenia. We analyzed nationwide survey data to determine the relationship between peak expiratory flow rate and sarcopenia in older Indonesians. Community-dwelling Indonesian individuals aged ≥60 years (n = 2422; mean age = 67.21 y) from the fifth-wave data of the Indonesian Family Life Survey was selected. Sarcopenia was diagnosed based on handgrip strength, gait speed, and appendicular skeletal muscle mass measurements. Peak expiratory flow rates (PEFRs) were categorized according to their percentage of predicted flow rates as <50%, 50% to 80%, and >80%. Confounders previously determined to be associated with sarcopenia occurrence were included. Sarcopenia prevalence was 50.25%. After adjustment for confounders, PEFRs of <50% and 50% to 80% were associated with an increased sarcopenia risk (odds ratio = 5.22 and 1.88, respectively) compared with PEFRs of >80%. Poor lung function was independently associated with sarcopenia occurrence. Future studies should explore the usefulness of PEFR as a risk factor of sarcopenia.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872226PMC
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0246179PLOS

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