Objective: The study intends to include the evaluation of family styles while the patients are admitted at a hospital dedicated to the emergency (SPDC).
Methods: The sample of the study involved patients of a SPDC and their families. The clinical assessment has been conducted through the use of ICD-IX, DSM-5 and BPRS. During the stabilization phase, both patients and families have been administered a socio-demographic report and the FACES IV. The FACES Questionnaire assesses the family through eight scales (two scales indicating health-oriented functioning: Balanced Cohesion, Balanced Flexibility; four scales indicating problematic functioning: Disengagement, Hyper-involvement, Rigidity, Disorganization; a scale for Family Communication; a scale for Family Satisfaction).
Results: 35,7% has shown to be health-oriented in the sample. Patients have shown a significantly higher problematic perception of their family, compared to their parents, being more involved in the relationship. The patients have a disengaged-disorganized family style, parents have an average-unbalanced style. The age of patients over 30 correlates significantly with a dysfunctional view of their family relationships.
Conclusions: Faced with an event that requires hospitalization, families have a greater tendency toward dysfunctionality, with a more painful perception than their children, partially counterbalanced by a greater functionality of the parents. The temporal element, the age of the patients and the duration of the illness seem significant elements in favor of a greater family problematic.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1708/3546.35218 | DOI Listing |
Cell Mol Life Sci
January 2025
Department of Anesthesiology, Shenzhen Children's Hospital, Yitian Road 7019, Shenzhen, 518000, China.
Hair follicle (HF) development and pigmentation are complex processes governed by various signaling pathways, such as TGF-β and FGF signaling pathways. Nestin + (neural crest like) stem cells are also expressed in HF stem cells, particularly in the bulge and dermal papilla region. However, the specific role and differentiation potential of these Nestin-positive cells within the HF remain unclear, especially regarding their contribution to melanocyte formation and hair pigmentation.
View Article and Find Full Text PDFCell Mol Biol (Noisy-le-grand)
January 2025
Department of Pharmacology, Faculty of Pharmacy, Mersin University, Mersin, Türkiye.
Increasing evidence suggests that inhibition of receptor-interacting serine/threonine-protein kinase (RIPK) 1/RIPK3/mixed lineage kinase domain-like pseudokinase (MLKL) necrosome has protective effects in vivo models of painful conditions seen in humans associated with inflammation and demyelination in the central nervous system. However, the contribution of RIPK1-driven necroptosis to inflammatory pain remains unknown. Therefore, this study aims to determine the effect of necrostatin (Nec) -1s, a selective RIPK1 inhibitor, on lipopolysaccharide (LPS)-induced inflammatory pain and related underlying mechanisms.
View Article and Find Full Text PDFClin Transl Med
January 2025
Allergy Center, Department of Otolaryngology, Affiliated Eye and ENT Hospital, Fudan University, Shanghai, China.
Background: House dust mite (HDM) is the leading allergen for allergic rhinitis (AR). Although allergic sensitisation by inhaled allergens renders susceptible individuals prone to developing AR, the molecular mechanisms driving this process remain incompletely elucidated.
Objective: This study aimed to elucidate the molecular mechanisms underlying HDM-induced AR.
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
January 2025
Department of Pathogen Biology and Immunology, Kunming Medical University, Kunming 650500, China. *Corresponding authors, E-mail:
The innate immune response is the first line of defense for the host against viral infections. Targeted degradation of pathogenic microorganisms through autophagy, in conjunction with pattern recognition receptors synergistically inducing the production of interferon (IFN), constitutes an important pathway for the body to resist viral infections. Rubicon, a Run domain Beclin 1-interacting and cysteine-rich domain protein, has an inhibitory effect on autophagy and IFN production.
View Article and Find Full Text PDFXi Bao Yu Fen Zi Mian Yi Xue Za Zhi
January 2025
Department of Blood Transfusion, First Affiliated Hospital of Nanyang Medical College, Nanyang 473003, China.
Objective To investigate the effect of basic helix-loop-helix family member E40 (BHLHE40) on the invasion and migration of osteosarcoma (OS) cells, and to explore the role of the phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT) signaling pathway in the biological behavior of OS mediated by BHLHE40, providing a scientific basis for targeted therapy of OS. Methods On the basis of clinical OS samples and OS cell lines, the expression differences of BHLHE40 between OS and adjacent tissues, as well as those between OS cells and normal osteoblast cell lines, were analyzed. BHLHE40 knockdown OS cells were obtained through shRNA transfection.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!