Laboratory results judged as unacceptable in external proficiency surveys do not always signal laboratory testing problems. This is a report of the results of a user's investigation of the proficiency testing flags encountered in our laboratory from three survey programs over a two-year period. The survey programs were administered by the College of American Pathologists, the Centers for Disease Control, and the State of New York. The explanations for the abnormal survey results were classified into six categories: possible analytic measurement problem (28%), clerical error in transcription or completion of forms (16%), inappropriate survey criteria (17%), specimen problem (11%), agency amended report (5%), and no identifiable cause (23%).
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PEC Innov
June 2025
Ariadne Labs at Brigham and Women's Hospital and Harvard T.H. Chan School of Public Health, 401 Park Dr, 3rd Floor, Boston, MA 02215, USA.
Background: Engaging patients in quality improvement and innovation projects is increasingly important, yet challenges persist with involving patients who speak languages other than English. This article presents design activities our team used to engage Spanish-speaking patients and cultural brokers.
Objective: To develop a clinician communication tool to enhance patient trust in pregnancy care clinicians, especially among minoritized populations who face language and cultural barriers, using human-centered design (HCD).
Biomedica
December 2024
Grupo Red de Donación y Trasplantes, Instituto Nacional de Salud, Bogotá, D. C., Colombia.
Introduction. The use of immunological tests before solid organ transplantation is essential to reduce the risk of rejection and post-transplant complications. Therefore, quality control systems in laboratories performing them are necessary for clinical practice.
View Article and Find Full Text PDFClin Chim Acta
January 2025
National Center for Clinical Laboratories, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital/ National Center of Gerontology, PR China. Electronic address:
Background: It is necessary and challenging to establish reasonable and feasible total error specifications for coagulation factor assays for quality control and assessment. The aim of this study is to establish new total error specifications for coagulation factor assays by combining External Quality Assessment data with reliable biological variation data.
Methods: Data from China National External Quality Assessment Scheme (28,408 results from 1,381 laboratories) were analyzed, stratifying External Quality Assessment data by reference intervals to establish concentration-dependent total error specifications.
Sci Rep
January 2025
Department of Quality Assurance and Laboratory Management, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Neurol Clin Pract
April 2025
Department of Neurology (AS), Massachusetts General Hospital, Harvard Medical School, Boston; Department of Public Health Sciences (RBAB), University of North Carolina at Charlotte; Disparities Research Unit, Department of Medicine, Massachusetts General Hospital; Department of Psychiatry, Harvard Medical School; Harvard Medical School (DH, SW), Boston; and City University of New York at Hunter College (DH, SW).
Background And Objectives: Limited English proficiency (LEP) impairs health access-including outpatient specialty care-and quality care, i.e., inappropriate use of diagnostic tests.
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