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Biological and Catalytic Activities of Green Synthesized Silver Nanoparticles from the Leaf Infusion of Boiss. | LitMetric
The discovery and development of active compounds to eliminate drug resistance and side effects is a crucial process. In this study, the leaf infusion of Boiss as a novel green alternative is used to synthesize silver nanoparticles (Drac-AgNPs). Antibacterial, cytotoxicity effects, hemocompatibility, and the catalytic properties of these nanoparticles are evaluated. The synthesis of Drac-AgNPs is confirmed by UV-vis spectroscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, and transmission electron microscopy, where Drac-AgNPs are spherical, with a size range of 5-63 nm. Their IC values against H1299 and MCF-7 cell lines are above 50 and 100 μg mL, respectively. Drac-AgNPs are effective against an inclusive range of the gram-positive and gram-negative bacteria, that is, , , , , , and , and a low hemolytic effect makes them an exceptional AgNP with a great hemocompatibility. They show a moderate catalytic-effect in terms of removing methylene blue, with 67% degradation. Altogether, Drac-AgNP, as a multi-tasker material, shows potential for the prevention and treatment of infections and photothermal/chemotherapy of cancers.
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