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| http://dx.doi.org/10.2169/internalmedicine.6602-20 | DOI Listing |
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A case of invasive mucinous adenocarcinoma presenting with massive bronchorrhea.
Respir Med Case Rep
July 2024
Department of Respiratory Medicine, Fukuoka University Chikushi Hospital, Fukuoka, Japan.
An 80-year-old non-smoking woman was admitted to hospital due to persistent sputum production and dyspnea. She developed respiratory failure, and chest imaging revealed multifocal consolidation and cavities. Her respiratory status did not respond to antimicrobial treatment and progressively worsened, with massive sputum production of approximately 1 L per day, and she died 19 days after admission.
View Article and Find Full Text PDFSuccessful treatment with osimertinib for nonmucinous bronchioloalveolar carcinoma with massive bronchorrhea and respiratory failure: a case report and literature review.
Transl Cancer Res
February 2023
Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Background: Correct diagnosis of bronchioloalveolar carcinoma (BAC) is often delayed due to the lack of familiarity with the condition among clinicians as its sporadic nature and its symptoms are similar to other respiratory issues. Among these, acute respiratory failure (ARF) caused by massive bronchorrhea is rarely associated with BAC. Here we first reported osimertinib in the treatment of BAC with bronchorrhea and ARF.
View Article and Find Full Text PDFBronchorrhea, a Rare and Debilitating Symptom of Lung Cancer: Case Report and Review of the Treatment.
JTO Clin Res Rep
October 2022
Department of Pulmonary and Critical Care Medicine, University of Tennessee, Knoxville, Tennessee.
Bronchorrhea, defined as production of voluminous watery sputum greater than 100 mL/d, is a debilitating symptom mostly found in end-stage lung cancer, specifically in invasive mucinous adenocarcinomas. Very rarely, it can primarily contribute to hypoxic respiratory failure and found in a critical care setting. We report a case of a 51-year-old woman diagnosed with having mucinous adenocarcinoma of the lung who presented to the intensive care unit with rapidly worsening respiratory failure and found to have massive bronchorrhea with daily sputum volume exceeding 1000 mL/d at its peak.
View Article and Find Full Text PDFMassive Bronchorrhea.
Intern Med
July 2021
Department of Internal Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan.
Pharmacological Management of Bronchorrhea in Malignant Disease: A Systematic Literature Review.
J Pain Symptom Manage
May 2016
Department of Palliative Medicine, Munich University Hospital, LMU Munich, Munich, Germany.
Context: Malignant respiratory tract tumors can lead to massive fluid production, known as bronchorrhea. This symptom can be very distressing itself, and it can lead to or aggravate other symptoms such as dyspnea and cough. Pharmacological treatment options have been reported in the literature.
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