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Perinatal depressive disorder prevalence in Africa: A systematic review and Bayesian analysis. | LitMetric

AI Article Synopsis

  • The study aimed to assess the prevalence of perinatal depression (PND) in Africa to address its significant impact on women's mental health.
  • Researchers analyzed data from various databases and found 154 studies covering over 113,000 women, using Bayesian modelling to estimate prevalence rates.
  • Results showed high rates of depressive disorder: 22.8% in pregnant women without specific conditions and as high as 44.6% in postpartum women with poor pregnancy outcomes, indicating a need for targeted preventive measures, especially for vulnerable groups like those with HIV.

Article Abstract

Objective: To curb the burden of perinatal depression (PND) in Africa, it is important to have an accurate estimate of its burden in the continent. Hence, we determined the prevalence of (major) depressive disorder in the perinatal period in Africa.

Methods: We searched PubMed, EMBASE, Africa Index Medicus, and Africa Journal Online, to identify studies reporting the prevalence of (major) depressive disorder in the perinatal period in Africa, between January 1st 2000 and February 17th 2020. PND prevalence was estimated using Bayesian modelling.

Results: We identified 154 studies (192 data points; 113,147 women). In pregnant women, the prevalence of depressive disorder was 22.8% (95%Credible interval [CrI]: 21.5-24.1) among women with no specific condition and 31.9% (95%CrI: 30.2-33.6) among those with HIV. In post-partum, the prevalence was 21.2% (95%CrI: 20.0-22.5), 30.0% (95%CrI: 28.2-31.8), and 44.6% (95%CrI: 35.9-53.8) among women with no specific condition, with HIV, and with poor pregnancy outcomes, respectively.

Conclusions: This study depicted a high prevalence of PND in Africa. This prevalence varied across pre-defined clinical profiles. HIV-infected women or those with poor pregnancy outcomes having a higher prevalence of depression. This highlights the need for more attention and preventive interventions geared towards these sub-groups.

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Source
http://dx.doi.org/10.1016/j.genhosppsych.2021.01.006DOI Listing

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