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Reductio ad absurdum in critical care trials.
J Crit Care
February 2021
HCor Research Institute, Rua Abílio Soares, 250, 12th Floor, São Paulo, Brazil. Electronic address:
Extraordinary claims require extraordinary evidence in asserted mtDNA biparental inheritance.
Forensic Sci Int Genet
July 2020
Institute of Genetic Epidemiology, Department of Genetics and Pharmacology, Medical University of Innsbruck, Innsbruck, 6020, Austria.
A breakthrough article published in PNAS by Luo et al. challenges a central dogma in biology which states that the mitochondrial DNA (mtDNA) in humans is inherited exclusively from the mother. We re-analyzed original FASTQ files and results reported by Luo et al.
View Article and Find Full Text PDFCommentary: The Need for Bayesian Hypothesis Testing in Psychological Science.
Front Psychol
August 2017
Business School, Massey UniversityPalmerston North, New Zealand.
Does reductio ad absurdum have a place in evidence-based medicine?
BMC Med
June 2014
INSERM, U669 Maison de Solenn, 97 Boulevard de Port Royal, Paris cedex 14, 75679, France.
In a meta-analysis published in BMC Medicine, we explored whether evidence-based medicine can actually be sure that 'sucrose = sucrose' in the treatment of depression. This paper, based upon a reductio ad absurdum, addressed an epistemological question using a 'scientific' approach, and could be disconcerting as suggested by Cipriani and Geddes' commentary. However, most papers are based upon a mixture of observations and discussions about sense and meaning.
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