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Innovative capsulation and microencapsulation of plant hormones: a strategy to combat plant pathogens.
Cell Mol Biol (Noisy-le-grand)
January 2025
Department of Biotechnology, Faculty of Agriculture, Tarbiat Modares University, Tehran, Iran.
One of the prevailing trends in contemporary agriculture is the application of biological control. Nevertheless, several reports suggest that biocontrol bacteria exhibit poor survival rates in host plants. Consequently, the concept of shielding biological control agents by encapsulating them in outer coatings has gained popularity.
View Article and Find Full Text PDFEngineered hypoxia-responsive albumin nanoparticles mediating mitophagy regulation for cancer therapy.
Nat Commun
January 2025
School of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-Sen University, Shenzhen, China.
Hypoxic tumors present a significant challenge in cancer therapy due to their ability to adaptation in low-oxygen environments, which supports tumor survival and resistance to treatment. Enhanced mitophagy, the selective degradation of mitochondria by autophagy, is a crucial mechanism that helps sustain cellular homeostasis in hypoxic tumors. In this study, we develop an azocalix[4]arene-modified supramolecular albumin nanoparticle, that co-delivers hydroxychloroquine and a mitochondria-targeting photosensitizer, designed to induce cascaded oxidative stress by regulating mitophagy for the treatment of hypoxic tumors.
View Article and Find Full Text PDFDevelopment of sustainable and active food packaging films based on alginate enriched with plant polyphenol carbon dots and layered clay.
Int J Biol Macromol
January 2025
Xiamen Meijiamei New Material Technology Co., Ltd., Xiamen 361110, PR China. Electronic address:
Natural polymer based food packaging has attracted more and more attention, but the lack of active functions of natural polymer hinders its application in the field of active packaging. In this study, chlorogenic acid carbon dots (CGA-CDs) was synthesized mildly using natural plant polyphenol CGA as carbon source, and CGA functionalized layered clays (LDHs@CGA) was introduced as reinforcing agent. Alg active films were fabricated by solution casting method using natural polysaccharide-alginate (Alg), CGA-CDs and LDHs@CGA.
View Article and Find Full Text PDFMelt electrowriting of amorphous solid dispersions: Influence of drug and plasticizer on rheology and printing performance.
Int J Pharm
January 2025
Soft Matter Chemistry, Department of Chemistry, and Helsinki Institute of Sustainability Science, Faculty of Science, University of Helsinki, PB55 00014 Helsinki, Finland. Electronic address:
Drug loaded microfiber scaffolds have potential for sublingual drug delivery due to their fast dissolution time and tunable porosity. Such microfiber scaffolds can be prepared by melt electrowriting (MEW), wherein a polymer melt is electrostatically drawn out of a syringe onto a computer controlled moving collector. The fabrication of such scaffolds via MEW has previously been shown for a polymer with a glass transition temperature (T) just above room temperature, making handling challenging.
View Article and Find Full Text PDFFirst evidence of molecular response of the shrimp Hippolyte inermis to biodegradable microplastics.
J Hazard Mater
December 2024
Stazione Zoologica Anton Dohrn, Department of Ecosustainable Marine Biotechnology, Ischia Marine Centre, Via Francesco Buonocore, 42, Ischia 80077, Italy.
The increasing demand for sustainable alternatives to conventional plastics has propelled the interest in bioplastics. A few papers reported on the effects of plastics on crustaceans, but no indication about biodegradable polymers is available. Hippolyte inermis Leach, 1816 is a protandric shrimp commonly living on leaves of the seagrass Posidonia oceanica, in the Mediterranean Sea.
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