Objective: To compare knee joint awareness following kinematic alignment (KA) TKA in patients who had previously undergone mechanical alignment (MA) on their contralateral knee.
Methods: We performed a retrospective study of all consecutive patients who underwent staged bilateral TKA, the first using MA technique and the second utilizing the KA technique, without patient specific instrumentations. Primary outcome was assessed by the Forgotten Joint Score (FJS) with a minimum 1-year follow-up. Differences between knees were also assessed by three predefined key questions. Secondary outcome were differences in knee alignment assessed by long standing x-rays.
Results: Overall, 38 patients (76 knees) met inclusion criteria and were included in the analysis. The mean time for follow up was significantly shorter (P < 0.01) in the KA knees (1.8 years, SD 0.3) compared to the MA knees (3.1 years, SD 0.8). Nonetheless, patients were significantly less aware of their KA knees compared to their MA knees; median FJS scores were 74.0 for the KA group (IQR¼ 54.5-92.0) and 67.0 for the MA group (IQR¼ 43.7-88.0) (p = 0.01). Overall, 31 patients (81.6%) preferred their KA knee over their MA knee 6 (15.8%) (p < 0.001). KA bone cuts resulted in net varus of the medial proximal tibia (86.9, SD 2.0) and valgus of the distal femur (86.6, SD 2.8). However, the overall alignment was similar (femorotibial angle 5.4 ± 2.3 vs. 4.7 ± 2.4, p = 0.45).
Conclusions: Patients who underwent staged bilateral knee arthroplasty were less aware of the knee that was kinematically aligned compared to the knee that was mechanically aligned. Future studies should focus on the long-term survivorship of KA TKA.
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http://dx.doi.org/10.1016/j.jor.2020.12.032 | DOI Listing |
Zhonghua Fu Chan Ke Za Zhi
January 2025
Department of Gynecology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing100021, China.
To analyze the clinical characteristics, treatments, and prognosis of patients with ovarian juvenile granulosa cell tumor (JGCT). Clinical and pathological data, and follow-up information of 34 patients diagnosed with JGCT from 2000 to 2021 were collected from the surveillance, epidemiology, and end results (SEER) database. A retrospective analysis was conducted to summarize the patients' clinical and pathological characteristics, treatments, and prognosis.
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January 2025
Department of Epidemiology and Health Statistics, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, Fujian, China
Aims: To investigate the associations between influencing factors with length of stay (LOS) and hospitalisation expenses in oral cancer (OC) patients, and to explore the potential pathways through which these factors influence hospitalisation expenses using path analysis.
Design: Cross-sectional.
Setting: A comprehensive tertiary hospital in southeastern China.
J Integr Neurosci
January 2025
Department of Radiology, Affiliated Hospital of North Sichuan Medical College, 637000 Nanchong, Sichuan, China.
Background: Volume alterations in the parietal subregion have received less attention in Alzheimer's disease (AD), and their role in predicting conversion of mild cognitive impairment (MCI) to AD and cognitively normal (CN) to MCI remains unclear. In this study, we aimed to assess the volumetric variation of the parietal subregion at different cognitive stages in AD and to determine the role of parietal subregions in CN and MCI conversion.
Methods: We included 662 participants from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database, including 228 CN, 221 early MCI (EMCI), 112 late MCI (LMCI), and 101 AD participants.
J Clin Med
January 2025
Department of Plastic, Reconstructive and Aesthetic Surgery and Hand Surgery, Centre Hospitalier Universitaire Vaudois (CHUV), 1011 Lausanne, Switzerland.
: Combining autologous fat grafting with implant placement is meant to improve the quality of implant-based breast reconstruction. The present study explores the concept of multi-stage composite breast reconstruction with repeated sessions of autologous fat grafting to increase mastectomy flap thickness and provide better pre-pectoral implant coverage. : Twenty-five consecutive patients underwent bilateral multi-stage composite expander-to-implant breast reconstruction and reverse expansion from August 2020 to April 2024.
View Article and Find Full Text PDFMolecules
January 2025
Institute of Polymers, Composites and Biomaterials, National Research Council (IPCB-CNR), Portici, 80055 Naples, Italy.
To obtain sustainable food packaging materials, alternatives to traditional ones must be researched. In this work, two different kinds of zeolites, i.e.
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