Chronic Thromboembolic Disease and Chronic Thromboembolic Pulmonary Hypertension.

Clin Chest Med

Department of Internal Medicine II, Division of Cardiology, Medical University of Vienna, Währinger Gürtel 18-20, Vienna 1090, Austria.

Published: March 2021

AI Article Synopsis

  • CTEPH and CTED are rare conditions that can develop after venous thromboembolism, likely sharing the same underlying mechanisms.
  • Both conditions may be effectively treated with procedures like pulmonary endarterectomy and balloon pulmonary angioplasty, as well as medications such as Riociguat and subcutaneous treprostinil.
  • These treatments can lead to significant improvement or near-cure for affected patients.

Article Abstract

Chronic thromboembolic pulmonary hypertension (CTEPH) and chronic thromboembolic pulmonary vascular disease (CTED) are rare manifestations of venous thromboembolism. Presumably, CTEPH and CTED are variants of the same pathophysiological mechanism. CTEPH and CTED can be near-cured by pulmonary endarterectomy, balloon pulmonary angioplasty, and medical treatment with Riociguat or subcutaneous treprostinil, which are the approved drugs.

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Source
http://dx.doi.org/10.1016/j.ccm.2020.11.014DOI Listing

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