Objective: To emulate a randomised controlled trial investigating whether lateral or mediolateral episiotomy compared with no episiotomy reduces the prevalence of obstetric anal sphincter injury (OASIS) in nulliparous women delivered with vacuum extraction.

Design: A population-based observational study.

Setting: Sweden.

Population: 63 654 nulliparous women delivered with vacuum extraction derived from the Swedish Medical Birth Register 2000-2011, with a live singleton baby with no known malformations in cephalic presentation in gestational week ≥34 , and subject to lateral or mediolateral episiotomy or no episiotomy.

Methods: The effect of episiotomy was calculated using a causal doubly robust estimation method based on propensity scores. Results are presented as the average treatment effect and numbers needed to treat (NNT).

Main Outcome Measures: OASIS (third- and fourth-degree perineal injury) in nulliparous women delivered with vacuum extraction.

Results: Episiotomy was associated with a reduction in OASIS from 15.5% to 11.8%, average treatment effect of -3.66% (95% CI -4.31 to -3.01) and NNT 27. Third-degree perineal injuries were reduced from 14.0% to 10.9% (-3.08, 95% CI -3.71 to -2.42) with NNT 32. Fourth-degree perineal injuries were reduced from 1.6% to 1.0 % (-0.58%, 95% CI -0.79 to -0.37) with NNT 172.

Conclusions: Lateral or mediolateral episiotomy reduced the prevalence of OASIS in nulliparous women delivered with vacuum extraction, compared to women with no episiotomy.

Tweetable Abstract: To prevent one case of OASIS in first-time mothers delivered with vacuum, 27 episiotomies had to be performed.

Download full-text PDF

Source
http://dx.doi.org/10.1111/1471-0528.16663DOI Listing

Publication Analysis

Top Keywords

delivered vacuum
20
nulliparous women
16
women delivered
16
vacuum extraction
12
lateral mediolateral
12
mediolateral episiotomy
12
obstetric anal
8
anal sphincter
8
sphincter injury
8
oasis nulliparous
8

Similar Publications

Selective coupling of C platform molecules to C olefins is a cornerstone for establishing a sustainable chemical industry based on nonpetroleum sources. Vinyl chloride (CHCl), one of the top commodity petrochemicals, is commercially produced from coal- or oil-derived C hydrocarbon (acetylene and ethylene) feedstocks with a high carbon footprint. Here, we report a C-based route for vinyl chloride synthesis via the selective oxidative coupling of methyl chloride.

View Article and Find Full Text PDF

Purpose: The aim of this study was to use calorimetry to understand the difference in energy transferred by three phacoemulsification surgical platforms to the eye.

Patients And Methods: A phacoemulsification tip was lowered into a double-walled calorimeter filled with distilled water. The foot pedal was depressed for 30 seconds and the change in temperature of the water was measured by a temperature probe.

View Article and Find Full Text PDF

Negative pressure wound therapy (NPWT) is a very effective method in the treatment of dehiscent, infected, and non-healing wounds. Difficult wound healing occurs especially in late pregnancy due to the rapid enlargement of the uterus and the constantly increasing tension of the entire abdominal wall. In cases of dehiscence of the surgical wound during pregnancy, proper subsequent treatment is needed, where it is necessary to consider the safety of the mother as well as the fetus.

View Article and Find Full Text PDF

Rationally designed universal passivator for high-performance single-junction and tandem perovskite solar cells.

Nat Commun

January 2025

State Key Laboratory of Reliability and Intelligence of Electrical Equipment, School of Materials Science and Engineering, Hebei University of Technology, Tianjin, China.

Interfacial trap-assisted nonradiative recombination hampers the development of metal halide perovskite solar cells (PSCs). Herein, we report a rationally designed universal passivator to realize highly efficient and stable single junction and tandem PSCs. Multiple defects are simultaneously passivated by the synergistic effect of anion and cation.

View Article and Find Full Text PDF

MoS-confined Rh-Zn atomic pair boosts photo-driven methane carbonylation to acetic acid.

Nat Commun

January 2025

State Key Laboratory of Physical Chemistry of Solid Surfaces, Collaborative Innovation Center of Chemistry for Energy Materials, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, China.

Direct carbonylation of CH to CHCOOH provides a promising pathway for upgrading of natural gas to transportable liquid chemicals, in which high-efficiency CH activation and controllable C-C coupling are both critical but challenging. Herein, we report that highly efficient photo-driven carbonylation of CH with CO and O to CHCOOH is achieved over MoS-confined Rh-Zn atomic-pair in conjunction with TiO. It delivers a high CHCOOH productivity of 152.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!