Despite the clinical emphasis on processes happening within individuals, investigations into the psychological, structural connections between mental health symptoms have almost exclusively analyzed differences between people. These investigations have revealed important findings; however, they do not reveal the close connections among symptoms in an individuals' psychology. This study thus examined the psychological connections between symptoms directly, using borderline personality disorder (BPD) symptoms as an example. Participants (252; 74 with BPD) reported their momentary BPD symptoms five times daily, and 165 did so again 18 months later. In support of personalized medicine (Wright & Woods, 2020), individuals' BPD symptom structures differed considerably from each other and from the between-person structure. A novel technique revealed that differences were greater than expected by chance. Within-person structures tended to exhibit more symptom granularity (more factors and lower variance explained) and differing symptom meanings (patterns of loadings). For example, some individuals exhibited close connections between relationship turmoil and identity uncertainty, whereas other individuals exhibited close connections between relationship turmoil and impulsivity. Thus, conceptions of any given person's psychopathological processes using between-person structural findings will most likely be inaccurate. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
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http://dx.doi.org/10.1037/abn0000656 | DOI Listing |
Int J Psychoanal
December 2024
Psychologist, Psychotherapist at CMPP de Courbevoie, Courbevoie, France.
In this article, the author aims to shed new light on how sensoriality can be considered and deployed in the treatment of severely autistic children. Whereas psychoanalysis has explored in detail the defensive function that sensoriality can have for these patients, the author puts forward the idea that this can be used to further the differentiation and structuration of the body ego. Through some detailed clinical material, drawn from the psychotherapy of a five-year-old girl, the author sets out to illustrate how work on the different sensations can lead to relational openings that are initially specific to each sensory channel and then more general, as well as how the access to otherness emerges from this work on sensations.
View Article and Find Full Text PDFPatient Educ Couns
December 2024
Philipps-Universität Marburg, Institut für Germanistische Sprachwissenschaft, Deutschhausstraße 3, Marburg 35032, Germany. Electronic address:
Objective: This paper studies argumentation and its function to establish common ground in pregnancy counseling conversations during the third trimester of the pregnancy, focusing on two material topoi: Non-comparability and Unplannability.
Methods: We take a conversation-analytical and interactional approach and draw on 37 natural occurring counseling conversations, videorecorded during two periods at a university hospital. The conversations are typically between the midwife and the pregnant woman.
J Colloid Interface Sci
January 2025
School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 510006 China; Guangdong Provincial Laboratory of Chemistry and Fine Chemical Engineering Jieyang Center, School of Advanced Manufacturing, Guangdong University of Technology, Jieyang 515200 China. Electronic address:
Extrusion-based printing of macroscopic architectures layer-by-layer offers new opportunities for constructing customized electromagnetic interference (EMI) shielding materials. However, current research primarily focuses on improving the printability of material inks by increasing contents and adding various modifiers, controllable construction of ultralight and robust macro-architectures with structural design at both macro- and micro-scales is still challenging. Herein, we develop a graphene oxide foaming ink enriched with air bubbles for direct-ink writing, enabling the creation of macroscopic graphene architectures with arbitrary geometries.
View Article and Find Full Text PDFJ Neurochem
January 2025
Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Canada.
Highly abundant in neurons, the cellular prion protein (PrP) is an obligatory precursor to the disease-associated misfolded isoform denoted PrP that accumulates in the rare neurodegenerative disorders referred to either as transmissible spongiform encephalopathies (TSEs) or as prion diseases. The ability of PrP to serve as a substrate for this template-mediated conversion process depends on several criteria but importantly includes the presence or absence of certain endoproteolytic events performed at the cell surface or in acidic endolysosomal compartments. The major endoproteolytic events affecting PrP are referred to as α- and β-cleavages, and in this review we outline the sites within PrP at which the cleavages occur, the mechanisms potentially responsible and their relevance to pathology.
View Article and Find Full Text PDFBackground: Mental health remains among the top 10 leading causes of disease burden globally, and there is a significant treatment gap due to limited resources, stigma, limited accessibility, and low perceived need for treatment. Problem Management Plus, a World Health Organization-endorsed brief psychological intervention for mental health disorders, has been shown to be effective and cost-effective in various countries globally but faces implementation challenges, such as quality control in training, supervision, and delivery. While digital technologies to foster mental health care have the potential to close treatment gaps and address the issues of quality control, their development requires context-specific, interdisciplinary, and participatory approaches to enhance impact and acceptance.
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