J Dermatolog Treat
Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Published: May 2022
Background: Biologic psoriasis treatments are differentiated by efficacy, side effects, and other attributes.
Objective: Determine attributes of biologic psoriasis treatments that drive patients' treatment choices.
Methods: Respondents (USA: = 300; Germany: = 300) with moderate-to-severe psoriasis completed a discrete-choice-experiment survey, choosing between hypothetical treatments characterized by attributes with varying levels: chance of clear skin after 1 year, number of first-year treatments, first-year risks of mild-to-moderate injection site reaction (ISR) and serious infection, and years of proven efficacy/safety.
Results: U.S. respondents most valued clear skin (conditional relative importance, 1.88; < .05). While other attributes were of generally equivalent importance, ISR risk outweighed serious-infection risk (1.06 vs. 0.70; < .05). German respondents placed greatest importance on ISR risk (1.61; < .05) and clear skin (1.49; < .05).
Limitations: Respondents evaluated hypothetical treatments and were recruited from web panels.
Conclusions: Clear skin and ISR risk are stronger drivers of treatment choice than injection frequency and infection risk.
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http://dx.doi.org/10.1080/09546634.2020.1839007 | DOI Listing |
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