This study aimed to evaluate psychological distress of persons in quarantine and compare the same with a group of persons, who are currently in lockdown. Forty-four persons in quarantine and 45 subjects currently in lockdown were evaluated on Depression Anxiety Stress Scale II. About three-fourth (77.3%) of the participants in the quarantine group and one-third (37.8%) in the comparator group had depression. About one fourth (22.7%) in the quarantine group and one-third (35.6%) in the lockdown group had anxiety. The present study suggests that lockdown and being in quarantine are associated with significantly higher psychiatric morbidity, especially anxiety.
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http://dx.doi.org/10.1055/s-0040-1718855 | DOI Listing |
J Eval Clin Pract
February 2025
Department of Psychology, University of Bologna, Bologna, Italy.
Background: In contrast to abundant research on the various acute mental effects of COVID-19, the long-term influences of the pandemic are still underexplored in China owing to the paucity of assessment tools. The Pandemic Disengagement Syndrome Scale (PDSS) assesses people's social disengagement as a lasting psychological consequence in Western countries during the post-COVID-19 pandemic era. However, its generalizability across cultures is untested.
View Article and Find Full Text PDFBMC Public Health
January 2025
Department of Epidemiology and Biostatistics, School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia.
Introduction: The 2019 COVID-19 pandemic had a global impact, leading to numerous deaths, long recovery times, and economic challenges worldwide, especially in countries with limited financial resources like Ethiopia. In Ethiopia, Hawassa lacks viral shedding information. Identifying predictors can help ease economic impact of illness.
View Article and Find Full Text PDFPolymers (Basel)
December 2024
School of Materials Science and Engineering, Changzhou University, Changzhou 213164, China.
Amide-amine (PAMAM) dendrimers are biodegradable, non-immunogenic, genotoxic, and biocompatibible, which make them excellent materials for biological applications. In order to reduce the cytotoxicity of the designed branched molecules, a four-armed branched nucleus (B4) of PAMAM dendrimers as hyperbranched molecules was fused with polyhexamethylene biguanide (PHMB) (A2); hyperbranched polymeric biguanides (PAPBs) with a four-arm central core PAMAM structure were synthesized. The bactericidal and cell toxicity tests showed that PAPB had excellent bactericidal activity against both Gram-positive bacteria and Gram-negative, and the chemical binding of PHMB and PAMAM had synergistic effects.
View Article and Find Full Text PDFInt J Environ Res Public Health
December 2024
Department of Human Neuroscience, Sapienza University of Rome, 00185 Rome, Italy.
Background: The lockdown due to the COVID-19 pandemic, imposed in many countries in 2021, led to social isolation and the interruption of many activities that were useful in stimulating cognition. The impact of these changes has been particularly severe in older subjects with cognitive impairment.
Methods: The present study aimed to investigate the effects of lockdown on Alzheimer's disease patients (in cognition, behavior, and autonomy) and on their caregivers (in emotions, burden, and quality of life).
Int J Pharm
January 2025
NMPA Key Laboratory for Safety Evaluation of Cosmetics, Guangdong Provincial Key Laboratory of Tropical Disease Research, Department of Hygiene Inspection & Quarantine Science, School of Public Health, Southern Medical University, Guangzhou, Guangdong 510515, China. Electronic address:
Diclofenac (DIC) is a nonsteroidal anti-inflammatory drug with poor tabletability and water solubility. In the present study, a new diclofenac-picolinamide cocrystal (DIC-PIC) was prepared to simultaneously improve its tabletability and solubility. The cocrystal was characterized using multiple techniques, such as X-ray diffraction, thermal methods and spectral analyses.
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