Context: Plantar fasciitis (PF) is a common condition in active individuals. The lack of agreement on PF etiology makes treatment challenging and highlights the importance of understanding risk factors for preventive efforts.
Objective: The purpose of this systematic review and meta-analysis was to determine what factors may put physically active individuals at risk of developing PF.
Data Sources: CENTRAL, CINAHL, EMBASE, Gray Lit, LILACS, MEDLINE (PubMed), ProQuest, Scopus, SPORTDiscus, and Web of Science were searched through April 2018 and updated in April 2020.
Study Selection: Studies were included if they were original research investigating PF risk factors, compared physically active individuals with and without PF, were written in English, and were accessible as full-length, peer-reviewed articles.
Study Design: Systematic review and meta-analysis.
Level Of Evidence: Level 3, because of inconsistent definitions and blinding used in the included observational studies.
Data Extraction: Data on sample characteristics, study design and duration, groups, PF diagnosis, and risk factors were extracted. The methodological quality of the studies was assessed using the Strengthening the Reporting of Observational Studies in Epidemiology statement. When means and standard deviations of a particular risk factor were presented 2 or more times, that risk factor was included in the meta-analysis.
Results: Sixteen studies were included in the systematic review and 11 risk factors in the meta-analysis. Increased plantarflexion range of motion (weighted mean difference [MD] = 7.04°; 95% CI, 5.88-8.19; < 0.001), body mass index (MD = 2.13 kg/m; 95% CI, 1.40-2.86; < 0.001; = 0.00%), and body mass (MD = 4.52 kg; 95% CI, 0.55-8.49; = 0.026) were risk factors for PF.
Conclusion: Interventions focused on addressing a greater degree of plantarflexion range of motion, body mass index, and body mass and their load on the force-absorbing plantar surface structures may be a good starting point in the prevention and treatment of active individuals with PF.
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http://dx.doi.org/10.1177/1941738120970976 | DOI Listing |
J Med Internet Res
March 2025
Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Background: Hypertension is a major global health issue and a significant modifiable risk factor for cardiovascular diseases, contributing to a substantial socioeconomic burden due to its high prevalence. In China, particularly among populations living near desert regions, hypertension is even more prevalent due to unique environmental and lifestyle conditions, exacerbating the disease burden in these areas, underscoring the urgent need for effective early detection and intervention strategies.
Objective: This study aims to develop, calibrate, and prospectively validate a 2-year hypertension risk prediction model by using large-scale health examination data collected from populations residing in 4 regions surrounding the Taklamakan Desert of northwest China.
Dermatol Reports
March 2025
Oncology Center, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong Province.
Skin cancer (SC) is a significant public health issue, with increasing incidence rates globally. Although environmental factors such as ultraviolet (UV) exposure are recognized risk factors, the impact of metabolites on SC development has not been thoroughly examined. This study seeks to explore the causal association between metabolites and SC risks using a Mendelian randomization (MR) approach.
View Article and Find Full Text PDFJAMA Netw Open
March 2025
Department of Psychiatry, University of Oxford, Oxford, United Kingdom.
Importance: Epidemiological studies suggest that lifestyle factors are associated with risk of dementia. However, few studies have examined the association of diet and waist to hip ratio (WHR) with hippocampus connectivity and cognitive health.
Objective: To ascertain how longitudinal changes in diet quality and WHR during midlife are associated with hippocampal connectivity and cognitive function in later life.
JAMA Netw Open
March 2025
Department of Epidemiology, University of North Carolina at Chapel Hill.
Importance: Numerous efforts have been made to include diverse populations in genetic studies, but American Indian populations are still severely underrepresented. Polygenic scores derived from genetic data have been proposed in clinical care, but how polygenic scores perform in American Indian individuals and whether they can predict disease risk in this population remains unknown.
Objective: To study the performance of polygenic scores for cardiometabolic risk factors of lipid traits and C-reactive protein in American Indian adults and to determine whether such scores are helpful in clinical prediction for cardiometabolic diseases.
JAMA Cardiol
March 2025
Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Importance: Food insecurity is associated with prevalent cardiovascular disease (CVD), but studies have been limited to cross-sectional data.
Objectives: To study whether food insecurity is associated with incident CVD and to determine whether this association varies by sex, education, or race.
Design, Setting, And Participants: This prospective cohort study was conducted among US adults without preexisting CVD participating in the CARDIA (Coronary Artery Risk Development in Young Adults) study from 2000 to August 31, 2020.
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