The COVID-19 pandemic has triggered outbreaks of unanticipated toxicities, including methanol toxicity. Multiple methanol outbreaks have been described, including contaminated hand sanitizer in the southwest USA. In this case, we describe a fatal case of methanol toxicity from hand sanitizer ingestion, geographically separated from the outbreak in the southwest USA and prior to the announcement of nationwide warnings by the Food and Drug Administration (FDA). The product was identified as one later recalled by the FDA for methanol contamination. Additionally, the consumption in this case was related to a desire to conceal alcohol consumption from family members. This case of methanol toxicity should increase awareness of the ease of which contaminated products can be widely distributed and of the use of alternative ethanol-containing products to obscure relapse in alcohol use disorder.
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http://dx.doi.org/10.1007/s13181-021-00824-9 | DOI Listing |
Turk J Pharm Sci
January 2025
University of Tlemcen, Faculty of Science, Department of Chemistry, Laboratory of Natural and Bioactive Substances, Tlemcen, Algeria.
Objectives: This study focused on the phytochemical, insecticidal, and bactericidal activities of Vahl, as well as molecular docking analysis of an acetylcholinesterase (AChE) inhibitor as a promising natural insecticide.
Materials And Methods: The leaves of were successively extracted with n-hexane, acetone, and methanol. Silica gel column chromatography of the methanol extract yielded compound 1.
J Travel Med
January 2025
School of Medicine, College of Medicine, Nursing and Health Sciences, University of Galway, Galway, Ireland.
Nutrients
December 2024
Department of Pharmacognosy with Medicinal Plant Garden, Medical University in Lublin, 1 Chodzki St., 20-093 Lublin, Poland.
: We assessed the influence of long-term injection of magnoflorine (MAG) on memory acquisition in mice for the first time. : This isoquinoline alkaloid that belongs to the aporphines was isolated from the roots of by centrifugal partition chromatography (CPC) using a biphasic solvent system composed of chloroform: methanol: water in the ratio 4:3:3 (//) with 20 mM of hydrochloric acid and triethylamine, within 64 min. : Our results indicated that long-term injection of MAG 20 mg/kg dose improve the long-term memory acquisition in mice that were evaluated in the passive avoidance (PA) test with no toxicity records.
View Article and Find Full Text PDFPlants (Basel)
December 2024
Laboratory of Entomology, Juana Díaz Agricultural Experiment Station, Department of Agro-Environmental Sciences, University of Puerto Rico, Mayaguez Campus, Mayaguez, PR 00681, USA.
Plant botanical extracts are recognized for being a source of biologically active phytochemicals that potentially have diverse applications. The phytochemical composition, potential cytotoxicity, and insecticidal effectiveness of three leaf extracts from the folkloric medicinal plant L. (Calophyllaceae) were investigated.
View Article and Find Full Text PDFJ Ethnopharmacol
January 2025
School of Pharmaceutical Sciences, Siksha 'O' Anusandhan Deemed to Be University, Bhubaneswar, 751003, Odisha, India. Electronic address:
Ethnopharmacological Relevance: Argemone mexicana L. (Papaveraceae), a weed that thrives in the tropical and subtropical areas of South and Central America, Mexico, Caribbean Islands and India. In India, it has been used traditionally to treat vesicular calculus, inflammatory conditions, and hepatobiliary disorders.
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