Workers of the ant have been previously shown to be able to add and subtract numbers of elements and to expect the time and location of the next food delivery. We wanted to know if they could anticipate the following quantity of elements present near their food when the number of these elements increases or decreases over time according to an arithmetic sequence. Two experiments were therefore carried out, one with an increasing sequence, the other with a decreasing sequence. Each experiment consisted of two steps, one for the ants to learn the numbers of elements successively present near their food, the other to test their choice when they were simultaneously in the presence of the numbers from a previously learned sequence and the following quantity. The ants anticipated the following quantity in each presented numerical sequence. This forethinking of the next quantity applies to numerosity, thus, to concrete items. This anticipatory behavior may be explained by associative learning and by the ants' ability to memorize events and to estimate the elapsing time.
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http://dx.doi.org/10.3390/bs11020018 | DOI Listing |
J Pharm Sci
December 2024
Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark. Electronic address:
Physiological and artificial solubilizing agents usually enhance apparent solubility of poorly soluble drugs, and in many cases also oral drug exposure. However, exposure may decrease in cases where micellization reduces the molecularly dissolved drug fraction, overriding the solubility advantage. While this information is critical to accurately anticipate the effect of drug micellization on oral absorption, the experimental determination of molecularly dissolved drug concentrations is complex and time consuming.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
December 2024
Nanjing University, Department of Biomedical Engineering, CHINA.
Biological systems utilize precise spatial organization to facilitate and regulate information transmission within signaling networks. Inspired by this, artificial scaffolds that enable delicate spatial arrangements are desirable to increase the local concentration of reactants, expedite specific interactions, and minimize undesired interference. In this study, we presented an integrated biosensing nanodevice, termed TRI-HCR, in which hybridization chain reaction (HCR) probes were precisely organized on a triangular DNA origami nanostructure (TRI) with finely-tuned distance, quantity, and pattern.
View Article and Find Full Text PDFGMS J Med Educ
December 2024
University Medical Center Hamburg-Eppendorf, University Children's Research, Hamburg, Germany.
Postgraduate medical education (PGME) is an essential part of medical education and increasingly shifts into focus of educational stakeholders. Structured postgraduate medical training programs are required in the U.S.
View Article and Find Full Text PDFFEBS J
December 2024
Department of Experimental and Clinical Medicine, University of Florence, Italy.
The advent of next-generation sequencing (NGS) technologies has made it possible to investigate microbial communities in various environments, including different sites within the human body. Therefore, the previously established belief of the sterile nature of several body sites, including human blood, has now been challenged. However, metagenomics investigation of areas with an anticipated low microbial biomass may be susceptible to misinterpretation.
View Article and Find Full Text PDFCell Tissue Bank
December 2024
The Center for Innovations and Biodesign, San Antonio, TX, USA.
Amniotic membrane is arguably one of the most popular biological wound dressings on the market today. Various growth factors and cytokines inherent to amniotic membrane tissue have been recognized as key mediators in wound healing and tissue regeneration, giving the tissue its clinical utility. Sterilization methodologies using irradiation are recognized as the gold standard in the field and routinely used to prepare tissue allografts, including amniotic membrane for transplantation.
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