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http://dx.doi.org/10.1111/pin.13070 | DOI Listing |
Pathol Int
April 2021
Department of Pathology, Chi-Mei Medical Center, Tainan, Taiwan.
Rev Med Chil
December 2018
Servicio de Medicina, Hospital Naval A. Nef., Viña del Mar, Chile.
We report a 23 year old woman presenting with a nephrotic syndrome due to minimal change disease, central diabetes insipidus, primary hypothyroidism, vitiligo and universal alopecia. Eleven years later, she presented secondary amenorrhea due to hypogonadotropic hypogonadism, with mild hyperprolactinemia and central adrenal insufficiency. A magnetic resonance imaging of the sella turcica showed a pituitary mass with suprasellar extension that was resected using a transsphenoidal approach.
View Article and Find Full Text PDFJ Gastroenterol
July 2010
Division of Gastroenterology and Hepatology, The Third Department of Internal Medicine, Kansai Medical University, 10-15 Fumizono, Moriguchi, Osaka, 570-8507, Japan.
Objectives: Patients with autoimmune pancreatitis (AIP) characteristically show elevated serum levels of immunoglobulin G4 (IgG4) and abundant infiltration of IgG4-positive plasmacytes in the involved organs. The most common involved organ showing extrapancreatic lesions is the bile duct, which exhibits sclerosing cholangitis (SC). However, the role of IgG4 in the development of IgG4-related SC (IgG4-SC) remains unclear.
View Article and Find Full Text PDFJ Biol Chem
June 1997
Geneva Biomedical Research Institute, GlaxoWellcome Research and Development, Immunology Department, 14, Chemin des Aulx, CH-1228 Plan les Ouates, Geneva, Switzerland.
Immunoglobulin (Ig) E production by B cells requires two primary signals provided by T cells, interleukin (IL)-4 or IL-13 and CD40 ligand (CD40L). In addition, costimulatory signals, such as CD23-CD21 interaction, contribute further ensuring a selective control over this production. Recently, CD28, expressed on T cells, has been reported to be involved in this process.
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