Direct access to -diethynylethenes is achieved by a Ni-catalyzed 3,3-dialkynylation of 2-aryl acrylamides with 1-bromotriisopropylsilylacetylene. The preliminary mechanism study reveals that the reaction goes through a sequential double vinylic C-H bond activation with the assistance of an 8-aminoquinolinyl directing group.
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| http://dx.doi.org/10.1021/acs.orglett.0c04137 | DOI Listing |
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