Aortic Sources of Embolism.

Front Neurol

Department of Neurology and Stroke Center, APHP Bichat Hospital, Paris, France Université de Paris, LVTS, Inserm U1148, Paris, France.

Published: January 2021

AI Article Synopsis

  • Aortic arch atheroma is common in ischemic stroke patients, but its exact role in causing strokes or as a sign of atherosclerosis is still unclear.
  • Transesophageal echocardiography is the best method for spotting it, with CT angiography as a strong alternative; other imaging techniques may help assess plaque risk.
  • While the best antithrombotic treatment is not yet determined, intensive lipid-lowering therapy is recommended, and the review aims to provide guidance on diagnosis and treatment based on current research.

Article Abstract

Aortic arch atheroma is a frequent finding in ischemic stroke patients. Its role as a source of cerebral emboli or a marker of atherosclerosis is unclear. Transesophageal echography is considered the gold standard for its detection, whereas computed tomography angiography is a good alternative; magnetic resonance and positron emission tomography could be proposed to better analyze plaque vulnerability. Despite the interest in this condition, the optimal antithrombotic treatment remains uncertain, while intensive lipid-lowering therapy should be recommended. This review aims to offer guidance on patients with aortic arch atheroma, about its causal role in stroke, diagnosis, and treatment based on current available evidence.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7843443PMC
http://dx.doi.org/10.3389/fneur.2020.606663DOI Listing

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