Necrotic enteritis caused by has reemerged as a severe poultry disease worldwide since the ban on the routine use of antibiotics in animal feed. Probiotics are considered alternatives to antibiotic growth promoters. species are the most common microorganisms used as probiotics in the feed industry. The current study investigated the growth and surfactin levels of in solid-state fermentation using different substrates and evaluated the effects of -fermented products on growth performance and intestinal morphology in broilers exposed to . The highest viable biomass and surfactin concentration of -fermented products was observed at 2% molasses and 20% soybean meal supplementation during fermentation (<0.05). -fermented product-derived surfactin inhibited the growth of in a dose dependent manner (<0.05). -fermented product supplementation (2 g/kg) significantly improved the body weight and average daily gain weight of broilers challenged with (<0.05). -fermented products significantly alleviated necrotic lesions and ameliorated intestinal morphology in broilers exposed to (<0.05). Collectively, these observations demonstrate that -fermented products improve growth performance and gut morphology in broilers under challenge. -fermented products may have the potential to be used as alternatives to antibiotic growth promoters for preventive treatments against in broilers.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837812PMC
http://dx.doi.org/10.2141/jpsa.0200010DOI Listing

Publication Analysis

Top Keywords

-fermented products
12
growth performance
8
performance intestinal
8
morphology broilers
8
products improve
4
growth
4
improve growth
4
intestinal gut
4
gut morphology
4
broilers challenge
4

Similar Publications

Impact of Positive Glucose, Lactose, and Fructose Hydrogen Breath Tests on Symptoms and Quality of Life in Irritable Bowel Syndrome.

J Gastroenterol Hepatol

January 2025

Faculty of Medicine, Division of Gastroenterology, Department of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.

Background: Gas production due to fermentation from fructose malabsorption (FM) or lactose malabsorption (LM) and small intestinal bacterial overgrowth (SIBO) contribute to the development of gastrointestinal symptoms in patients with irritable bowel syndrome (IBS). However, the impact of the carbohydrate malabsorption, unlike SIBO, is relatively unknown.

Methodology: A multicenter, prospective study of consecutive adults with IBS who underwent a hydrogen breath test (HBT) (glucose, 75 g; lactose, 25 g; or fructose, 25 g) was conducted.

View Article and Find Full Text PDF

Ginkgo biloba (G. biloba) exocarp, a by-product of seed production, is produced in an amount of over 75,000 tons annually in China. However, due to the lack of suitable processing methods, it is predominantly discarded as agricultural waste, resulting in substantial waste of resource.

View Article and Find Full Text PDF

Up-flow anaerobic sludge blanket bioreactor for the production of carboxylates: effect of inocula on process performance and microbial communities.

Bioresour Bioprocess

January 2025

Biotechnology Processes Unit, IMDEA Energy, Avda. Ramón de la Sagra 3, Móstoles, Madrid, 28935, Spain.

This research investigated the acidogenic fermentation (AF) of sugar cane molasses in an up-flow anaerobic sludge blanket (UASB) reactor for the production of carboxylates. The first step was to assess the optimum process temperature (25, 35 or 55 ºC) using two different granular inocula, one from a brewery company (BGS) and other from a paper plant company (PGS). These experiments determined that the most suitable temperature for carboxylates production was 25 ºC, obtaining higher bioconversions (27.

View Article and Find Full Text PDF

Resistance to drugs is one of the major issues affecting the response to pharmacological treatments for tumors. Different mechanisms have been proposed to explain the development of cancer drug resistance (CDR), and several approaches to overcome it have been suggested. However, the biological basis of CDR remains unclear.

View Article and Find Full Text PDF

L-asparaginase (asparagine amidohydrolase) contributes to 40% of the total enzyme demands worldwide and is one-third of the global requirement as an anti-cancerous drug in treating acute lymphocytic leukemia (ALL), a type of leukemia. This protein breaks down L-asparagine into aspartic acid and ammonia those involved in ALL, rely on for growth and survival. Both non-recombinant and recombinant L-asparaginase can be produced by bacteria when a suitable substrate and method (solid-state fermentation (SSF) or submerged fermentation (SmF) which are techniques to grow microorganisms under controlled conditions), is provided.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!