A fractional compartmental mathematical model for the spread of the COVID-19 disease is proposed. Special focus has been done on the transmissibility of super-spreaders individuals. Numerical simulations are shown for data of Galicia, Spain, and Portugal. For each region, the order of the Caputo derivative takes a different value, that is not close to one, showing the relevance of considering fractional models.
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http://dx.doi.org/10.1016/j.chaos.2021.110652 | DOI Listing |
Arch Bronconeumol
December 2024
Pulmonology Service, Cruces University Hospital (OSI EEC), Barakaldo, Spain; BioBizkaia Health Research Institute, Spain.
The Spanish Society of Pneumology and Thoracic Surgery (SEPAR) and the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) have developed together Clinical Practice Guidelines (GPC) on the management of people affected by tuberculosis (TB) resistant to drugs with activity against Mycobacterium tuberculosis. These clinical practice guidelines include the latest updates of the SEPAR regulations for the diagnosis and treatment of drug-resistant TB from 2017 and 2020 as the starting point. The methodology included asking relevant clinical questions based on PICO methodology, a literature search focusing on each question, and a systematic and comprehensive evaluation of the evidence, with a summary of this evidence for each question.
View Article and Find Full Text PDFAlzheimers Res Ther
January 2025
Center for Cognitive and Computational Neuroscience, Complutense University of Madrid, Pozuelo de Alarcón, 28223, Spain.
Background: Changes in amyloid beta (Aβ) and phosphorylated tau brain levels are known to affect brain network organization but very little is known about how plasma markers can relate to these measures. We aimed to address the relationship between centrality network changes and two plasma pathology markers: phosphorylated tau at threonine 231 (p-tau231), a proxy for early Aβ change, and neurofilament light chain (Nfl), a marker of axonal degeneration.
Methods: One hundred and four cognitively unimpaired individuals were divided into a high pathology load (33 individuals; HP) group and a low pathology (71 individuals; LP) one.
Mol Oncol
January 2025
Sarcoma Research Group, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Oncobell, L'Hospitalet de Llobregat, Barcelona, Spain.
Ewing sarcoma (EWS) is the second most common bone tumor affecting children and young adults, with dismal outcomes for patients with metastasis at diagnosis. Mechanisms leading to metastasis remain poorly understood. To deepen our knowledge on EWS progression, we have profiled tumors and metastases from a spontaneous metastasis mouse model using a multi-omics approach.
View Article and Find Full Text PDFBMC Plant Biol
January 2025
Misión Biológica de Galicia (CSIC), Depto. Producción Vegetal, Pazo de Salcedo, Carballeira 8, Pontevedra, 36143, Spain.
Background: The crosslinking of maize cell wall components, particularly mediated by the formation of ferulic acid dimers or diferulates, has been associated with important crop valorization traits such as increased pest resistance, lower forage digestibility, or reduced bioethanol production. However, these relationships were based on studies performed using diverse unrelated inbred lines and/or populations, so genetic background could interfere on these associations.
Results: In the present research, the success of a pedigree selection program aimed to obtain inbred lines from a common antecessor with contrasting diferulate concentration was evaluated.
Spectrochim Acta A Mol Biomol Spectrosc
December 2024
Group EcoPast (GI-1553), CRETUS, Area of Archaeology, Dpt of History, Universidade de Santiago de Compostela, Santiago de Compostela, 15782, Spain; Archaeological Research Laboratory, Stockholm University, Wallenberglaboratoriet, SE-10691 Stockholm, Sweden. Electronic address:
Several studies have used Fourier Transform Infrared Spectroscopy (FTIR) to assess chemical and structural changes caused by diagenesis in archaeological human bone, whereas other factors such as individual's biological profile (sex and age) or the type of bone have seldom been considered. In this study transmission FTIR was applied to 51 bone samples from 19 post-Roman individuals of A Lanzada necropolis (NW Spain). Mid-infrared (MIR) indices (IRSF, MMI, C/P, C/C, Am/P, BPI, API, AmI/AmII) were also calculated and principal component analysis (PCA) was used to explore peak ratios and differences across the whole spectrum.
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